Anti-IP6K2 Antibody (CAB13427)
- SKU:
- CAB13427
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
| Antibody Name: | Anti-IP6K2 Antibody |
| Antibody SKU: | CAB13427 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | IF |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human IP6K2 (NP_057375.2). |
| Application: | IF |
| Recommended Dilution: | IF 1:50 - 1:200 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human IP6K2 (NP_057375.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSPA FRAM DVEP RAKG VLLE PFVH QVGG HSCV LRFN ETTL CKPL VPRE HQFY ETLP AEMR KFTP QYKG VVSV RFEE DEDR NLCL IAYP LKGD HGIV DIVD NSDC EPKS KLLR WTTN KKHH VLET EKTP KDWV RQHR KEEK MKSH KLEE EFEW LKKS EVLY YTVE KKGN ISSQ LKHY NPWS |
| Gene ID: | 51447 |
| Uniprot: | Q9UHH9 |
| Cellular Location: | Nucleus |
| Calculated MW: | 8kDa/9kDa/11kDa/20kDa/21kDa/49kDa |
| Observed MW: |
| Synonyms: | IP6K2, IHPK2, PIUS |
| Background: | This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1, 3, 4, 5, 6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| UniProt Protein Function: | IHPK2: Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Belongs to the inositol phosphokinase (IPK) family. 5 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Kinase, other; Motility/polarity/chemotaxis; EC 2.7.4.21 Chromosomal Location of Human Ortholog: 3p21.31 Cellular Component: intermediate filament cytoskeleton; nucleoplasm; nucleus Molecular Function:inositol 1,3,4,5,6-pentakisphosphate kinase activity; inositol heptakisphosphate kinase activity; inositol hexakisphosphate kinase activity; protein binding Biological Process: inositol phosphate metabolic process; negative regulation of cell growth; phosphoinositide phosphorylation; positive regulation of apoptosis |
| NCBI Summary: | This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9UHH9 |
| NCBI GenInfo Identifier: | 50400688 |
| NCBI Gene ID: | 51447 |
| NCBI Accession: | Q9UHH9.2 |
| UniProt Secondary Accession: | Q9UHH9,Q6P0N8, Q9BSZ6, Q9BUW3, Q9H4P7, Q9NT63, Q9UFU6 A8K3B1, B4E3G6, G8JLL6, |
| UniProt Related Accession: | Q9UHH9 |
| Molecular Weight: | 9,825 Da |
| NCBI Full Name: | Inositol hexakisphosphate kinase 2 |
| NCBI Synonym Full Names: | inositol hexakisphosphate kinase 2 |
| NCBI Official Symbol: | IP6K2 |
| NCBI Official Synonym Symbols: | PIUS; IHPK2 |
| NCBI Protein Information: | inositol hexakisphosphate kinase 2 |
| UniProt Protein Name: | Inositol hexakisphosphate kinase 2 |
| UniProt Synonym Protein Names: | P(i)-uptake stimulator; PiUS |
| Protein Family: | Inositol hexakisphosphate kinase |
| UniProt Gene Name: | IP6K2 |
| UniProt Entry Name: | IP6K2_HUMAN |
 | Immunofluorescence analysis of A549 cells using IP6K2 antibody (CAB13427). Blue: DAPI for nuclear staining. |