Anti-IL-17C Antibody (CAB10587)
- SKU:
- CAB10587
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
| Antibody Name: | IL17C Rabbit Polyclonal Antibody |
| Antibody SKU: | CAB10587 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-197 of human IL17C (NP_037410.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, HepG2, HT-29, Mouse small intestine, Rat lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-197 of human IL17C (NP_037410.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | HHDP SLRG HPHS HGTP HCYS AEEL PLGQ APPH LLAR GAKW GQAL PVAL VSSL EAAS HRGR HERP SATT QCPV LRPE EVLE ADTH QRSI SPWR YRVD TDED RYPQ KLAF AECL CRGC IDAR TGRE TAAL NSVR LLQS LLVL RRRP CSRD GSGL PTPG AFAF HTEF IHVP VGCT CVLP RSV |
| Gene ID: | 27189 |
| Uniprot: | Q9P0M4 |
| Cellular Location: | Secreted |
| Calculated MW: | 21kDa |
| Observed MW: | 25kDa |
| Synonyms: | IL17C, CX2, IL-17C |
| Background: | The protein encoded by this gene is a T cell-derived cytokine that shares the sequence similarity with IL17. This cytokine was reported to stimulate the release of tumor necrosis factor alpha and interleukin 1 beta from a monocytic cell line. The expression of this cytokine was found to be restricted to activated T cells. |
| UniProt Protein Function: | IL17C: Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1. Belongs to the IL-17 family. |
| UniProt Protein Details: | Protein type:Cytokine; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 16q24.2 Cellular Component: extracellular region Biological Process: cell surface receptor linked signal transduction; cell-cell signaling |
| NCBI Summary: | The protein encoded by this gene is a T cell-derived cytokine that shares the sequence similarity with IL17. This cytokine was reported to stimulate the release of tumor necrosis factor alpha and interleukin 1 beta from a monocytic cell line. The expression of this cytokine was found to be restricted to activated T cells. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9P0M4 |
| NCBI GenInfo Identifier: | 20138769 |
| NCBI Gene ID: | 27189 |
| NCBI Accession: | Q9P0M4.1 |
| UniProt Secondary Accession: | Q9P0M4,Q3MIG8, Q9HC75, |
| UniProt Related Accession: | Q9P0M4 |
| Molecular Weight: | 22kDa |
| NCBI Full Name: | Interleukin-17C |
| NCBI Synonym Full Names: | interleukin 17C |
| NCBI Official Symbol: | IL17C |
| NCBI Official Synonym Symbols: | CX2; IL-17C |
| NCBI Protein Information: | interleukin-17C |
| UniProt Protein Name: | Interleukin-17C |
| UniProt Synonym Protein Names: | Cytokine CX2 |
| Protein Family: | Interleukin |
| UniProt Gene Name: | IL17C |
 | Western blot analysis of extracts of various cell lines, using IL17C antibody (CAB10587) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 20s. |
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