Anti-IFNA1 Antibody (CAB0285)
- SKU:
- CAB0285
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
| Antibody Name: | Anti-IFNA1 Antibody |
| Antibody SKU: | CAB0285 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-155 of human IFNA1 (NP_076918.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:100 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HL-60, Mouse liver, Rat liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-155 of human IFNA1 (NP_076918.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | DLPE THSL DNRR TLML LAQM SRIS PSSC LMDR HDFG FPQE EFDG NQFQ KAPA ISVL HELI QQIF NLFT TKDS SAAW DEDL LDKF CTEL YQQL NDLE ACVM QEER VGET PLMN ADSI LAVK KYFR RITL YLT |
| Gene ID: | 3439 |
| Uniprot: | P01562 |
| Cellular Location: | Secreted |
| Calculated MW: | 21kDa |
| Observed MW: | 21kDa |
| Synonyms: | IFNA1, IFL, IFN, IFN-ALPHA, IFN-alphaD, IFNA13, IFNA |
| Background: | The protein encoded by this gene is produced by macrophages and has antiviral activity. This gene is intronless and the encoded protein is secreted. |
| UniProt Protein Function: | IFNA1/13: a cytokine that belongs to the alpha/beta interferon family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 9p22 Cellular Component: extracellular space; extracellular region Molecular Function:interferon-alpha/beta receptor binding; cytokine activity Biological Process: B cell proliferation; adaptive immune response; cytokine and chemokine mediated signaling pathway; regulation of MHC class I biosynthetic process; humoral immune response; T cell activation during immune response; response to exogenous dsRNA; B cell differentiation; natural killer cell activation during immune response; innate immune response; blood coagulation; defense response to virus; positive regulation of peptidyl-serine phosphorylation of STAT protein |
| NCBI Summary: | The protein encoded by this gene is produced by macrophages and has antiviral activity. This gene is intronless and the encoded protein is secreted. [provided by RefSeq, Sep 2011] |
| UniProt Code: | P01562 |
| NCBI GenInfo Identifier: | 124455 |
| NCBI Gene ID: | 3439 |
| NCBI Accession: | P01562.1 |
| UniProt Secondary Accession: | P01562,Q14605, Q2M1L8, Q52LB8, Q5VYQ2, Q7M4Q1, Q8WZ68 Q9UMJ3, D4Q9M8, |
| UniProt Related Accession: | P01562 |
| Molecular Weight: | 21,725 Da |
| NCBI Full Name: | Interferon alpha-1/13 |
| NCBI Synonym Full Names: | interferon, alpha 1 |
| NCBI Official Symbol: | IFNA1 |
| NCBI Official Synonym Symbols: | IFL; IFN; IFNA@; IFNA13; IFN-ALPHA; IFN-alphaD |
| NCBI Protein Information: | interferon alpha-1/13; leIF D; IFN-alpha 1b; IFN-alpha-1/13; interferon-alpha1; interferon alpha-D; interferon alpha 1b |
| UniProt Protein Name: | Interferon alpha-1/13 |
| UniProt Synonym Protein Names: | Interferon alpha-D |
| Protein Family: | Mitochondrial brown fat uncoupling protein |
| UniProt Gene Name: | IFNA1 |
| UniProt Entry Name: | IFNA1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using IFNA1 antibody (CAB0285) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
 | Immunofluorescence analysis of A549 cells using IFNA1 antibody (CAB0285). Blue: DAPI for nuclear staining. |
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