Anti-ICAM1 Antibody (CAB20472)
- SKU:
- CAB20472
- Product type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- MAL
- CD54
- Icam
- Ly-4
- Ly-47
- Icam-1
- MALA-2
Description
| Product Name: | ICAM1 Rabbit pAb |
| Product Code: | CAB20472 |
| Size: | 50uL, 100uL |
| Synonyms: | MAL, CD54, Icam, Ly-4, Ly-47, Icam-1, MALA-2 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of Mouse ICAM1. |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Rat lung |
| Immunogen: | Recombinant protein of Mouse ICAM1. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 15894 |
| Uniprot: | P13597 |
| Calculated MW: | 58kDa |
| Observed MW: | 85KDa |
| UniProt Protein Function: | ICAM1: a type I membrane protein of the immunoglobulin superfamily. Is a ligand for the leukocyte adhesion LFA-1 protein (Integrin alpha-L/beta-2) and a Rhinovirus receptor. Typically expressed on endothelial cells and cells of the immune system. ICAM1 binds to integrins of type CD11a / CD18, or CD11b / CD18. Its expression is activated by p53 in an NF-kappaB-independent manner. Induced by TNFalpha in a process that involves IKKbeta. |
| UniProt Protein Details: | Protein type:Cell adhesion; Membrane protein, integral; Immunoglobulin superfamily Cellular Component: extracellular space; cell surface; focal adhesion; membrane; integral to plasma membrane; integral to membrane; plasma membrane; immunological synapse; external side of plasma membrane; lipid raft Molecular Function:integrin binding; protein complex binding Biological Process: regulation of cell adhesion; virion attachment, binding of host cell surface receptor; negative regulation of calcium ion transport; positive regulation of nitric oxide biosynthetic process; T cell antigen processing and presentation; activation of NF-kappaB transcription factor; positive regulation of cellular extravasation; regulation of cell shape; cell-cell adhesion; leukocyte adhesion; positive regulation of peptidyl-tyrosine phosphorylation; sensory perception of sound; positive regulation of actin filament polymerization; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; positive regulation of vasoconstriction; adhesion to host; cell adhesion mediated by integrin; cell adhesion; acute inflammatory response to antigenic stimulus |
| NCBI Summary: | This gene encodes an integral membrane protein that binds leukocyte adhesion protein LFA-1. It participates in the innate immune response. [provided by RefSeq, Aug 2016] |
| UniProt Code: | P13597 |
| NCBI GenInfo Identifier: | 124099 |
| NCBI Gene ID: | 15894 |
| NCBI Accession: | P13597.1 |
| UniProt Related Accession: | P13597 |
| Molecular Weight: | |
| NCBI Full Name: | Intercellular adhesion molecule 1 |
| NCBI Synonym Full Names: | intercellular adhesion molecule 1 |
| NCBI Official Symbol: | Icam1 |
| NCBI Official Synonym Symbols: | CD54; Ly-47; Icam-1; MALA-2 |
| NCBI Protein Information: | intercellular adhesion molecule 1 |
| UniProt Protein Name: | Intercellular adhesion molecule 1 |
| UniProt Synonym Protein Names: | MALA-2; MyD10; CD_antigen: CD54 |
| UniProt Gene Name: | Icam1 |
| UniProt Entry Name: | ICAM1_MOUSE |
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