Anti-HSPA6 Antibody (CAB7688)
- SKU:
- CAB7688
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
| Antibody Name: | Anti-HSPA6 Antibody |
| Antibody SKU: | CAB7688 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 474-643 of human HSPA6 (NP_002146.2). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Jurkat, Mouse heart, Rat brain, Rat heart |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 474-643 of human HSPA6 (NP_002146.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | PQIE VTFD IDAN GILS VTAT DRST GKAN KITI TNDK GRLS KEEV ERMV HEAE QYKA EDEA QRDR VAAK NSLE AHVF HVKG SLQE ESLR DKIP EEDR RKMQ DKCR EVLA WLEH NQLA EKEE YEHQ KREL EQIC RPIF SRLY GGPG VPGG SSCG TQAR QGDP STGP IIEE VD |
| Gene ID: | 3310 |
| Uniprot: | P17066 |
| Cellular Location: | |
| Calculated MW: | 71kDa |
| Observed MW: | 71kDa |
| Synonyms: | HSPA6, HSP70B |
| Background: |
| UniProt Protein Function: | HSPA6: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. Belongs to the heat shock protein 70 family. |
| UniProt Protein Details: | Protein type:Heat shock protein Chromosomal Location of Human Ortholog: 1q23 Cellular Component: centriole; cytoplasm; cytosol; signalosome Molecular Function:ATPase activity, coupled; enzyme binding; heat shock protein binding; protein binding; unfolded protein binding Biological Process: protein refolding; response to unfolded protein |
| UniProt Code: | P17066 |
| NCBI GenInfo Identifier: | 34978357 |
| NCBI Gene ID: | 3310 |
| NCBI Accession: | P17066.2 |
| UniProt Secondary Accession: | P17066,Q1HBA8, Q8IYK7, Q9BT95, |
| UniProt Related Accession: | P17066 |
| Molecular Weight: | 71,028 Da |
| NCBI Full Name: | Heat shock 70 kDa protein 6 |
| NCBI Synonym Full Names: | heat shock protein family A (Hsp70) member 6 |
| NCBI Official Symbol: | HSPA6 |
| NCBI Official Synonym Symbols: | HSP70B' |
| NCBI Protein Information: | heat shock 70 kDa protein 6 |
| UniProt Protein Name: | Heat shock 70 kDa protein 6 |
| UniProt Synonym Protein Names: | Heat shock 70 kDa protein B' |
| Protein Family: | Heat shock 70 kDa protein |
| UniProt Gene Name: | HSPA6 |
| UniProt Entry Name: | HSP76_HUMAN |
 | Western blot analysis of extracts of various cell lines, using HSPA6 antibody (CAB7688) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
 | Immunohistochemistry of paraffin-embedded human liver using HSPA6 Rabbit pAb (CAB7688) at dilution of 1:100 (40x lens). |
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