Anti-HOXB4 Antibody (CAB16878)
- SKU:
- CAB16878
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
Antibody Name: | Anti-HOXB4 Antibody |
Antibody SKU: | CAB16878 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human, Mouse |
Host Species: | Rabbit |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human HOXB4 (NP_076920.1). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human, Mouse |
Positive Samples: | HL-60, Mouse liver |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human HOXB4 (NP_076920.1). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | PEAG FGRR AACT VQRY AACR DPGP PPPP PPPP PPPP PPGL SPRA PAPP PAGA LLPE PGQR CEAV SSSP PPPP CAQN PLHP SPSH SACK EPVV YPWM RKVH V |
Gene ID: | 3214 |
Uniprot: | P17483 |
Cellular Location: | |
Calculated MW: | |
Observed MW: | 38kDa |
Synonyms: | HOXB4, HOX-2.6, HOX2, HOX2F |
Background: | This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion. |
UniProt Protein Function: | HOXB4: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Antp homeobox family. Deformed subfamily. |
UniProt Protein Details: | Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 17q21.32 Biological Process: positive regulation of transcription from RNA polymerase II promoter |
NCBI Summary: | This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion. [provided by RefSeq, Jul 2008] |
UniProt Code: | P17483 |
NCBI GenInfo Identifier: | 547692 |
NCBI Gene ID: | 3214 |
NCBI Accession: | P17483.2 |
UniProt Secondary Accession: | P17483,Q9NTA0, |
UniProt Related Accession: | P17483 |
Molecular Weight: | 27,604 Da |
NCBI Full Name: | Homeobox protein Hox-B4 |
NCBI Synonym Full Names: | homeobox B4 |
NCBI Official Symbol: | HOXB4 |
NCBI Official Synonym Symbols: | HOX2; HOX2F; HOX-2.6 |
NCBI Protein Information: | homeobox protein Hox-B4 |
UniProt Protein Name: | Homeobox protein Hox-B4 |
UniProt Synonym Protein Names: | Homeobox protein Hox-2.6; Homeobox protein Hox-2F |
Protein Family: | Homeobox protein |
UniProt Gene Name: | HOXB4 |