Anti-HLX Antibody (CAB7436)
- SKU:
- CAB7436
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
| Antibody Name: | Anti-HLX Antibody |
| Antibody SKU: | CAB7436 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-280 of human HLX (NP_068777.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | HL-60, Raji, THP-1, 293T |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-280 of human HLX (NP_068777.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | HPHA SFQA AARS PLRP TPVV APSE VPAG FPQR LSPL SAAY HHHH PQQQ QQQQ QPQQ QQPP PPPR AGAL QPPA SGTR VVPN PHHS GSAP APSS KDLK FGID RILS AEFD PKVK EGNT LRDL TSLL TGGR PAGV HLSG LQPS AGQF FASL DPIN EASA ILSP LNSN PRNS VQHQ FQDT FPGP YAVL TKDT MPQT YKRK RSWS R |
| Gene ID: | 3142 |
| Uniprot: | Q14774 |
| Cellular Location: | Nucleus |
| Calculated MW: | 50kDa |
| Observed MW: | 51kDa |
| Synonyms: | HLX, HB24, HLX1 |
| Background: |
| UniProt Protein Function: | HLX: Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. Involved in embryogenesis and hematopoiesis. Belongs to the H2.0 homeobox family. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 1q41 Cellular Component: nucleus Molecular Function:protein binding; sequence-specific DNA binding Biological Process: negative regulation of T-helper 2 cell differentiation; skeletal muscle development; transcription, DNA-dependent; regulation of transcription, DNA-dependent; embryonic digestive tract morphogenesis; multicellular organismal development; positive regulation of cell proliferation; liver development; cell differentiation; positive regulation of T-helper 1 cell differentiation; enteric nervous system development; positive regulation of organ growth |
| UniProt Code: | Q14774 |
| NCBI GenInfo Identifier: | 160291960 |
| NCBI Gene ID: | 3142 |
| NCBI Accession: | Q14774.3 |
| UniProt Secondary Accession: | Q14774,Q15988, Q59HE7, Q9NZ75, B2R8A8, |
| UniProt Related Accession: | Q14774 |
| Molecular Weight: | 488 |
| NCBI Full Name: | H2.0-like homeobox protein |
| NCBI Synonym Full Names: | H2.0-like homeobox |
| NCBI Official Symbol: | HLX |
| NCBI Official Synonym Symbols: | HB24; HLX1 |
| NCBI Protein Information: | H2.0-like homeobox protein; H2.0-like homeobox 1; H2.0-like homeo box 1; H2.0-like homeo box-1; homeobox protein HB24; homeobox protein HLX1 |
| UniProt Protein Name: | H2.0-like homeobox protein |
| UniProt Synonym Protein Names: | Homeobox protein HB24; Homeobox protein HLX1 |
| Protein Family: | H2.0-like homeobox protein |
| UniProt Gene Name: | HLX |
| UniProt Entry Name: | HLX_HUMAN |
 | Western blot analysis of extracts of various cell lines, using HLX antibody (CAB7436) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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