Anti-HKDC1 Antibody (CAB16573)
- SKU:
- CAB16573
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
| Antibody Name: | Anti-HKDC1 Antibody |
| Antibody SKU: | CAB16573 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human HKDC1 (NP_079406.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | U-251MG, A-549, 293T, SW620 |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human HKDC1 (NP_079406.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LGLT FSFP CRQT KLEE GVLL SWTK KFKA RGVQ DTDV VSRL TKAM RRHK DMDV DILA LVND TVGT MMTC AYDD PYCE VGVI IGTG TNAC YMED MSNI DLVE G |
| Gene ID: | 80201 |
| Uniprot: | Q2TB90 |
| Cellular Location: | |
| Calculated MW: | 82kDa/90kDa/102kDa |
| Observed MW: | 120kDa |
| Synonyms: | HKDC1 |
| Background: | This gene encodes a member of the hexokinase protein family. The encoded protein is involved in glucose metabolism, and reduced expression may be associated with gestational diabetes mellitus. High expression of this gene may also be associated with poor prognosis in hepatocarcinoma. |
| UniProt Protein Function: | HKDC1: Belongs to the hexokinase family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 2.7.1.1; Kinase, other Chromosomal Location of Human Ortholog: 10q22.1 Cellular Component: cytosol; mitochondrion Molecular Function:ATP binding; fructokinase activity; glucokinase activity; glucose binding; mannokinase activity Biological Process: carbohydrate phosphorylation; cell glucose homeostasis; glucose 6-phosphate metabolic process; glycolytic process; hexose metabolic process |
| NCBI Summary: | This gene encodes a member of the hexokinase protein family. The encoded protein is involved in glucose metabolism, and reduced expression may be associated with gestational diabetes mellitus. High expression of this gene may also be associated with poor prognosis in hepatocarcinoma. [provided by RefSeq, Sep 2016] |
| UniProt Code: | Q2TB90 |
| NCBI GenInfo Identifier: | 156151420 |
| NCBI Gene ID: | 80201 |
| NCBI Accession: | NP_079406.3 |
| UniProt Secondary Accession: | Q2TB90,Q2TB91, Q5VTC7, Q7Z373, Q8WU37, Q96EH2, Q9H5Y9 B5MDN9, |
| UniProt Related Accession: | Q2TB90 |
| Molecular Weight: | 82,682 Da |
| NCBI Full Name: | putative hexokinase HKDC1 |
| NCBI Synonym Full Names: | hexokinase domain containing 1 |
| NCBI Official Symbol: | HKDC1 |
| NCBI Protein Information: | putative hexokinase HKDC1 |
| UniProt Protein Name: | Putative hexokinase HKDC1 |
| UniProt Synonym Protein Names: | Hexokinase domain-containing protein 1 |
| Protein Family: | Putative hexokinase |
| UniProt Gene Name: | HKDC1 |
 | Western blot analysis of extracts of various cell lines, using HKDC1 antibody (CAB16573) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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