Anti-HAUS1 Antibody (CAB17250)
- SKU:
- CAB17250
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| Antibody Name: | Anti-HAUS1 Antibody |
| Antibody SKU: | CAB17250 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-250 of human HAUS1 (NP_612452.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-250 of human HAUS1 (NP_612452.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | NDLT SDLF RTKS KSEE IKIE LEKL EKNL TATL VLEK CLQE DVKK AELH LSTE RAKV DNRR QNMD FLKA KSEE FRFG IKAA EEQL SARG MDAS LSHQ SLVA LSEK LARL KQQT IPLK KKLE SYLD LMPN PSL |
| Gene ID: | 115106 |
| Uniprot: | Q96CS2 |
| Cellular Location: | |
| Calculated MW: | 32kDa |
| Observed MW: | Refer to figures |
| Synonyms: | HAUS1, CCDC5, HEI-C, HEIC, HsT1461 |
| Background: | HAUS1 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare, ' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]). |
| UniProt Protein Function: | Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. |
| NCBI Summary: | HAUS1 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM, Jun 2010] |
| UniProt Code: | Q96CS2 |
| NCBI GenInfo Identifier: | 19923971 |
| NCBI Gene ID: | 115106 |
| NCBI Accession: | NP_612452.1 |
| UniProt Secondary Accession: | Q96CS2,Q8N837, B2RDM7, |
| UniProt Related Accession: | Q96CS2 |
| Molecular Weight: | 22,744 Da |
| NCBI Full Name: | HAUS augmin-like complex subunit 1 |
| NCBI Synonym Full Names: | HAUS augmin like complex subunit 1 |
| NCBI Official Symbol: | HAUS1 |
| NCBI Official Synonym Symbols: | HEIC; CCDC5; HEI-C; HsT1461 |
| NCBI Protein Information: | HAUS augmin-like complex subunit 1 |
| UniProt Protein Name: | HAUS augmin-like complex subunit 1 |
| UniProt Synonym Protein Names: | Coiled-coil domain-containing protein 5; Enhancer of invasion-cluster; HEI-C |
| Protein Family: | HAUS augmin-like complex |
| UniProt Gene Name: | HAUS1 |
 | Western blot analysis of extracts of various cell lines, using HAUS1 antibody (CAB17250) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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