Anti-GYS1 Antibody (CAB8912)
- SKU:
- CAB8912
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Antibody Name: | Anti-GYS1 Antibody |
Antibody SKU: | CAB8912 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | A synthesized peptide derived from human Glycogen synthase |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | HeLa, 293T, RD, Mouse brain, Rat heart |
Immunogen: | A synthesized peptide derived from human Glycogen synthase |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 2997 |
Uniprot: | P13807 |
Cellular Location: | |
Calculated MW: | 84kDa |
Observed MW: | 85KDa |
Synonyms: | GSY, GYS |
Background: | The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1, 4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] |
UniProt Protein Function: | GYS1: muscle glycogen synthase 1. Transfers glucosyl residue from UDP-glucose to glycogen. Regulated allosterically by glucose-6-phosphate, and by PKA-mediated phosphorylation. |
UniProt Protein Details: | Protein type:Carbohydrate Metabolism - starch and sucrose; EC 2.4.1.11; Transferase Chromosomal Location of Human Ortholog: 19q13.3 Cellular Component: membrane; cytoplasm; inclusion body; cytosol Molecular Function:protein binding; glycogen (starch) synthase activity; protein kinase binding; glucose binding Biological Process: glycogen biosynthetic process; heart development; carbohydrate metabolic process; glucose metabolic process; pathogenesis Disease: Glycogen Storage Disease 0, Muscle |
NCBI Summary: | The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] |
UniProt Code: | P13807 |
NCBI GenInfo Identifier: | 1351366 |
NCBI Gene ID: | 2997 |
NCBI Accession: | P13807.2 |
UniProt Secondary Accession: | P13807,Q9BTT9, |
UniProt Related Accession: | P13807 |
Molecular Weight: | 737 |
NCBI Full Name: | Glycogen |
NCBI Synonym Full Names: | glycogen synthase 1 (muscle) |
NCBI Official Symbol: | GYS1 |
NCBI Official Synonym Symbols: | GSY; GYS |
NCBI Protein Information: | glycogen [starch] synthase, muscle; glycogen [starch] synthase, muscle |
UniProt Protein Name: | Glycogen [starch] synthase, muscle |
Protein Family: | Glycogen [starch] synthase |
UniProt Gene Name: | GYS1 |
UniProt Entry Name: | GYS1_HUMAN |