Anti-GTPBP1 Antibody (CAB15359)
- SKU:
- CAB15359
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-GTPBP1 Antibody |
| Antibody SKU: | CAB15359 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 10-280 of human GTPBP1 (NP_004277.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:200 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | U-251MG, Jurkat, HeLa, LO2, Mouse thymus |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 10-280 of human GTPBP1 (NP_004277.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MDSP VPAS MFAP EPSS PGAA RAAA AAAR LHGG FDSD CSED GEAL NGEP ELDL TSKL VLVS PTSE QYDS LLRQ MWER MDEG CGET IYVI GQGS DGTE YGLS EADM EASY ATVK SMAE QIEA DVIL LRER QEAG GRVR DYLV RKRV GDND FLEV RVAV VGNV DAGK STLL GVLT HGEL DNGR GFAR QKLF RHKH EIES GRTS SVGN DILG FDSE GNVV NKPD SHGG SLEW TKIC EKST KVIT FIDL AGHE KYLK TTVF GMTG HLPD FCML MVG |
| Gene ID: | 9567 |
| Uniprot: | O00178 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 72kDa |
| Observed MW: | 72kDa |
| Synonyms: | GTPBP1, GP-1, GP1, HSPC018 |
| Background: | This gene is upregulated by interferon-gamma and encodes a protein that is a member of the AGP11/GTPBP1 family of GTP-binding proteins. A structurally similar protein has been found in mouse, where disruption of the gene for that protein had no observable phenotype. |
| UniProt Protein Function: | GTPBP1: Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity. Belongs to the GTPBP1 GTP-binding protein family. |
| UniProt Protein Details: | Protein type:Hydrolase Chromosomal Location of Human Ortholog: 22q13.1 Cellular Component: cytosol; intracellular; membrane Molecular Function:GTPase activity; translation elongation factor activity Biological Process: immune response; signal transduction; translational elongation |
| NCBI Summary: | This gene is upregulated by interferon-gamma and encodes a protein that is a member of the AGP11/GTPBP1 family of GTP-binding proteins. A structurally similar protein has been found in mouse, where disruption of the gene for that protein had no observable phenotype. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O00178 |
| NCBI GenInfo Identifier: | 152031617 |
| NCBI Gene ID: | 9567 |
| NCBI Accession: | O00178.3 |
| UniProt Secondary Accession: | O00178,Q6IC67, |
| UniProt Related Accession: | O00178 |
| Molecular Weight: | 72,454 Da |
| NCBI Full Name: | GTP-binding protein 1 |
| NCBI Synonym Full Names: | GTP binding protein 1 |
| NCBI Official Symbol: | GTPBP1 |
| NCBI Official Synonym Symbols: | GP1; GP-1; HSPC018 |
| NCBI Protein Information: | GTP-binding protein 1 |
| UniProt Protein Name: | GTP-binding protein 1 |
| Protein Family: | GTP-binding protein |
| UniProt Gene Name: | GTPBP1 |
| UniProt Entry Name: | GTPB1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GTPBP1 antibody (CAB15359) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3s. |
Related Products
Anti-GTPBP10 Antibody (CAB20591)
