Anti-GSTT2 Antibody (CAB15678)
- SKU:
- CAB15678
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-GSTT2 Antibody |
| Antibody SKU: | CAB15678 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-244 of human GSTT2 (NP_000845.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | LO2, Mouse heart, Mouse kidney, Mouse liver, Rat liver, Rat kidney, Rat lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-244 of human GSTT2 (NP_000845.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MGLE LFLD LVSQ PSRA VYIF AKKN GIPL ELRT VDLV KGQH KSKE FLQI NSLG KLPT LKDG DFIL TESS AILI YLSC KYQT PDHW YPSD LQAR ARVH EYLG WHAD CIRG TFGI PLWV QVLG PLIG VQVP KEKV ERNR TAMD QALQ WLED KFLG DRPF LAGQ QVTL ADLM ALEE LMQP VALG YELF EGRP RLAA WRGR VEAF LGAE LCQE AHSI ILSI LEQA AKKT LPTP SPEA YQAM LLRI ARIP |
| Gene ID: | 2953 |
| Uniprot: | P0CG29 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 27kDa |
| Observed MW: | 27kDa |
| Synonyms: | GSTT2 |
| Background: | The protein encoded by this gene, glutathione S-transferase (GST) theta 2 (GSTT2), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT2 and GSTT2B are nearly identical to each other, and share 55% amino acid identity with GSTT1. All three genes may play a role in human carcinogenesis. The GSTT2 gene is a pseudogene in some populations. |
| UniProt Protein Function: | GST2: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity. Belongs to the GST superfamily. Theta family. |
| UniProt Protein Details: | Protein type:EC 2.5.1.18 Chromosomal Location of Human Ortholog: 22q11.23 Cellular Component: cytoplasm Molecular Function:glutathione transferase activity Biological Process: glutathione metabolic process |
| NCBI Summary: | The protein encoded by this gene, glutathione S-transferase (GST) theta 2 (GSTT2), is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT2 and GSTT2B are nearly identical to each other, and share 55% amino acid identity with GSTT1. All three genes may play a role in human carcinogenesis. The GSTT2 gene is a pseudogene in some populations. [provided by RefSeq, Sep 2015] |
| UniProt Code: | P0CG29 |
| NCBI GenInfo Identifier: | 300680960 |
| NCBI Gene ID: | 2953 |
| NCBI Accession: | P0CG29.1 |
| UniProt Secondary Accession: | P0CG29,O60665, P30712, Q6IPV7, Q9HD76, |
| UniProt Related Accession: | P0CG29 |
| Molecular Weight: | 27,506 Da |
| NCBI Full Name: | Glutathione S-transferase theta-2 |
| NCBI Synonym Full Names: | glutathione S-transferase theta 2 (gene/pseudogene) |
| NCBI Official Symbol: | GSTT2 |
| NCBI Protein Information: | glutathione S-transferase theta-2 |
| UniProt Protein Name: | Glutathione S-transferase theta-2 |
| UniProt Synonym Protein Names: | GST class-theta-2 |
| Protein Family: | Glutathione S-transferase |
| UniProt Gene Name: | GSTT2 |
| UniProt Entry Name: | GST2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GSTT2 antibody (CAB15678) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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