Anti-GSTO1 Antibody (CAB4636)
- SKU:
- CAB4636
- Product type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- GSTO 1-1
- GSTTLp28
- HEL-S-21
- P28
- SPG-R
Frequently bought together:
Description
| Product Name: | GSTO1 Rabbit mAb |
| Product Code: | CAB4636 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | GSTO 1-1, GSTTLp28, HEL-S-21, P28, SPG-R |
| Applications: | WB |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human GSTO1 |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Rat |
| Positive Samples: | HeLa, Jurkat, U-251MG, LO2, Rat liver, Rat brain |
| Immunogen: | A synthesized peptide derived from human GSTO1 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 9446 |
| Uniprot: | P78417 |
| Calculated MW: | 28kDa |
| Observed MW: | 30KDa |
| UniProt Protein Function: | GSTO1: Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid. Belongs to the GST superfamily. Omega family. |
| UniProt Protein Details: | Protein type:EC 1.8.5.1; Transferase; EC 1.20.4.2; Xenobiotic Metabolism - metabolism by cytochrome P450; EC 2.5.1.18; Other Amino Acids Metabolism - glutathione; Xenobiotic Metabolism - drug metabolism - cytochrome P450 Chromosomal Location of Human Ortholog: 10q25.1 Cellular Component: cytoplasm; cytosol Molecular Function:glutathione dehydrogenase (ascorbate) activity; glutathione transferase activity; methylarsonate reductase activity; oxidoreductase activity; protein binding Biological Process: glutathione metabolic process; L-ascorbic acid metabolic process; methylation; positive regulation of skeletal muscle contraction via regulation of the release of sequestered calcium ion; xenobiotic catabolic process |
| NCBI Summary: | The protein encoded by this gene is an omega class glutathione S-transferase (GST) with glutathione-dependent thiol transferase and dehydroascorbate reductase activities. GSTs are involved in the metabolism of xenobiotics and carcinogens. The encoded protein acts as a homodimer and is found in the cytoplasm. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010] |
| UniProt Code: | P78417 |
| NCBI GenInfo Identifier: | 6016173 |
| NCBI Gene ID: | 9446 |
| NCBI Accession: | P78417.2 |
| UniProt Secondary Accession: | P78417,Q5TA03, Q7Z3T2, D3DRA3, F5H7H0, |
| UniProt Related Accession: | P78417 |
| Molecular Weight: | 24,796 Da |
| NCBI Full Name: | Glutathione S-transferase omega-1 |
| NCBI Synonym Full Names: | glutathione S-transferase omega 1 |
| NCBI Official Symbol: | GSTO1 |
| NCBI Official Synonym Symbols: | P28; SPG-R; GSTO 1-1; GSTTLp28; HEL-S-21 |
| NCBI Protein Information: | glutathione S-transferase omega-1 |
| UniProt Protein Name: | Glutathione S-transferase omega-1 |
| UniProt Synonym Protein Names: | Glutathione S-transferase omega 1-1; GSTO 1-1; Glutathione-dependent dehydroascorbate reductase (EC:1.8.5.1 |
| Protein Family: | Glutathione S-transferase |
| UniProt Gene Name: | GSTO1 |
| UniProt Entry Name: | GSTO1_HUMAN |
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