Anti-GNGT2 Antibody (CAB9818)
- SKU:
- CAB9818
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-GNGT2 Antibody |
| Antibody SKU: | CAB9818 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-69 of human GNGT2 (NP_113686.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse eye |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-69 of human GNGT2 (NP_113686.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MAQD LSEK DLLK MEVE QLKK EVKN TRIP ISKA GKEI KEYV EAQA GNDP FLKG IPED KNPF KEKG GCLI S |
| Gene ID: | 2793 |
| Uniprot: | O14610 |
| Cellular Location: | Cell membrane, Cytoplasmic side, Lipid-anchor |
| Calculated MW: | 7kDa |
| Observed MW: | 14kDa |
| Synonyms: | GNGT2, G-GAMMA-8, G-GAMMA-C, GNG8, GNG9, GNGT8 |
| Background: | Phototransduction in rod and cone photoreceptors is regulated by groups of signaling proteins. The encoded protein is thought to play a crucial role in cone phototransduction. It belongs to the G protein gamma family and localized specifically in cones. Several transcript variants encoding the same protein have been found for this gene. |
| UniProt Protein Function: | G-gamma t2: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Belongs to the G protein gamma family. |
| UniProt Protein Details: | Protein type:G protein; G protein, heterotrimeric; G protein, heterotrimeric gamma Chromosomal Location of Human Ortholog: 17q21.32 Cellular Component: heterotrimeric G-protein complex; plasma membrane Molecular Function:GTPase activity |
| NCBI Summary: | Phototransduction in rod and cone photoreceptors is regulated by groups of signaling proteins. The encoded protein is thought to play a crucial role in cone phototransduction. It belongs to the G protein gamma family and localized specifically in cones. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2010] |
| UniProt Code: | O14610 |
| NCBI GenInfo Identifier: | 3023844 |
| NCBI Gene ID: | 2793 |
| NCBI Accession: | O14610.1 |
| UniProt Secondary Accession: | O14610,B2R746, D3DTW5, |
| UniProt Related Accession: | O14610 |
| Molecular Weight: | 8kDa |
| NCBI Full Name: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 |
| NCBI Synonym Full Names: | G protein subunit gamma transducin 2 |
| NCBI Official Symbol: | GNGT2 |
| NCBI Official Synonym Symbols: | GNG8; GNG9; GNGT8; G-GAMMA-8; G-GAMMA-C |
| NCBI Protein Information: | guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 |
| UniProt Protein Name: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 |
| UniProt Synonym Protein Names: | G gamma-C; G-gamma-8; G-gamma-9; Guanine nucleotide binding protein gamma transducing activity polypeptide 2 |
| UniProt Gene Name: | GNGT2 |
 | Western blot analysis of extracts of Mouse eye, using GNGT2 Rabbit pAb (CAB9818) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 20s. |
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