Anti-GNB5 Antibody (CAB4447)
- SKU:
- CAB4447
- Product type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- GNB5
- GB5
- IDDCA
- LADCI
Frequently bought together:
Description
| Product Name: | GNB5 Rabbit pAb |
| Product Code: | CAB4447 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | GNB5, GB5, IDDCA, LADCI |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human GNB5 (NP_006569.1). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Jurkat, HL-60, 293T, Mouse brain, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human GNB5 (NP_006569.1). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MATE GLHE NETL ASLK SEAE SLKG KLEE ERAK LHDV ELHQ VAER VEAL GQFV MKTR RTLK GHGN KVLC MDWC KDKR RIVS SSQD GKVI VWDS FTTN KEHA VTMP CTWV MACA YAPS GCAI ACGG LDNK CSVY PLTF DKNE NMAA KKKS VAMH TNYL SACS FTNS DMQI LTAS GDGT CALW DVES GQLL QSFH GHGA DVLC |
| Gene ID: | 10681 |
| Uniprot: | O14775 |
| Calculated MW: | 31kDa/38kDa/43kDa |
| Observed MW: | 39kDa |
| UniProt Protein Function: | G-beta 5: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Belongs to the WD repeat G protein beta family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:G protein, heterotrimeric beta Chromosomal Location of Human Ortholog: 15q21.2 Cellular Component: plasma membrane; nucleus Molecular Function:GTPase activity; G-protein gamma-subunit binding; signal transducer activity; protein binding; chaperone binding Biological Process: rhodopsin mediated signaling; phototransduction, visible light; regulation of rhodopsin mediated signaling; metabolic process; signal transduction |
| NCBI Summary: | Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternatively spliced transcript variants encoding different isoforms exist. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O14775 |
| NCBI GenInfo Identifier: | 38258891 |
| NCBI Gene ID: | 10681 |
| NCBI Accession: | O14775.2 |
| UniProt Secondary Accession: | O14775,Q9HAU9, Q9UFT3, B2RBR5, |
| UniProt Related Accession: | O14775 |
| Molecular Weight: | 395 |
| NCBI Full Name: | Guanine nucleotide-binding protein subunit beta-5 |
| NCBI Synonym Full Names: | guanine nucleotide binding protein (G protein), beta 5 |
| NCBI Official Symbol: | GNB5 |
| NCBI Official Synonym Symbols: | GB5 |
| NCBI Protein Information: | guanine nucleotide-binding protein subunit beta-5; gbeta5; transducin beta chain 5; G protein, beta-5 subunit; G protein, beta subunit 5L; guanine nucleotide-binding protein, beta subunit 5L |
| UniProt Protein Name: | Guanine nucleotide-binding protein subunit beta-5 |
| UniProt Synonym Protein Names: | Gbeta5; Transducin beta chain 5 |
| Protein Family: | Guanine nucleotide-binding protein |
| UniProt Gene Name: | GNB5 |
| UniProt Entry Name: | GBB5_HUMAN |
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