Anti-GNA14 Antibody (CAB10405)
- SKU:
- CAB10405
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-GNA14 Antibody |
| Antibody SKU: | CAB10405 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-350 of human GNA14 (NP_004288.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | BxPC-3, 293T, Mouse stomach, Mouse lung, Rat kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-350 of human GNA14 (NP_004288.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LLGT GESG KSTF IKQM RIIH GSGY SDED RKGF TKLV YQNI FTAM QAMI RAMD TLRI QYVC EQNK ENAQ IIRE VEVD KVSM LSRE QVEA IKQL WQDP GIQE CYDR RREY QLSD SAKY YLTD IDRI ATPS FVPT QQDV LRVR VPTT GIIE YPFD LENI IFRM VDVG GQRS ERRK WIHC FESV TSII FLVA LSEY DQVL AECD NENR MEES KALF KTII TYPW FLNS SVIL FLNK KDLL EEKI MYSH LISY FPEY TGPK QDVR AARD FILK LYQD QNPD KEKV IYSH FTCA TDTD NIRF VFAA VKDT ILQL NLR |
| Gene ID: | 9630 |
| Uniprot: | O95837 |
| Cellular Location: | |
| Calculated MW: | 41kDa |
| Observed MW: | 41kDa |
| Synonyms: | GNA14 |
| Background: | This gene encodes a member of the guanine nucleotide-binding, or G protein family. G proteins are heterotrimers consisting of alpha, beta and gamma subunits. The encoded protein is a member of the alpha family of G proteins, more specifically the alpha q subfamily of G proteins. The encoded protein may play a role in pertussis-toxin resistant activation of phospholipase C-beta and its downstream effectors. |
| UniProt Protein Function: | G-alpha 14: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Belongs to the G-alpha family. G(q) subfamily. |
| UniProt Protein Details: | Protein type:G protein, heterotrimeric alpha G(q); G protein; G protein, heterotrimeric Chromosomal Location of Human Ortholog: 9q21 Cellular Component: heterotrimeric G-protein complex; plasma membrane Molecular Function:GTPase activity; protein binding Biological Process: dopamine receptor, phospholipase C activating pathway; platelet activation; signal transduction |
| NCBI Summary: | This gene encodes a member of the guanine nucleotide-binding, or G protein family. G proteins are heterotrimers consisting of alpha, beta and gamma subunits. The encoded protein is a member of the alpha family of G proteins, more specifically the alpha q subfamily of G proteins. The encoded protein may play a role in pertussis-toxin resistant activation of phospholipase C-beta and its downstream effectors.[provided by RefSeq, Feb 2009] |
| UniProt Code: | O95837 |
| NCBI GenInfo Identifier: | 6016102 |
| NCBI Gene ID: | 9630 |
| NCBI Accession: | O95837.1 |
| UniProt Secondary Accession: | O95837,B1ALW3, |
| UniProt Related Accession: | O95837 |
| Molecular Weight: | 41,571 Da |
| NCBI Full Name: | Guanine nucleotide-binding protein subunit alpha-14 |
| NCBI Synonym Full Names: | G protein subunit alpha 14 |
| NCBI Official Symbol: | GNA14 |
| NCBI Protein Information: | guanine nucleotide-binding protein subunit alpha-14 |
| UniProt Protein Name: | Guanine nucleotide-binding protein subunit alpha-14 |
| Protein Family: | Guanine nucleotide-binding protein |
| UniProt Gene Name: | GNA14 |
| UniProt Entry Name: | GNA14_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GNA14 antibody (CAB10405) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
 | Immunofluorescence analysis of NIH/3T3 cells using GNA14 antibody (CAB10405) at dilution of 1:100. Blue: DAPI for nuclear staining. |
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