Anti-GM130 Antibody (CAB11408)
- SKU:
- CAB11408
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| Antibody Name: | Anti-GM130 Antibody |
| Antibody SKU: | CAB11408 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human GM130 |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, HepG2, Mouse brain, Rat brain |
| Immunogen: | A synthesized peptide derived from human GM130 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 2801 |
| Uniprot: | Q08379 |
| Cellular Location: | |
| Calculated MW: | 130kDa |
| Observed MW: | 130KDa |
 | Western blot - GM130 Rabbit mAb (CAB11408) |
| Synonyms: | GM130 |
| Background: | The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This encoded protein has been postulated to play roles in the stacking of Golgi cisternae and in vesicular transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Feb 2010] |
| UniProt Protein Function: | GM130: Golgi auto-antigen; probably involved in maintaining cis-Golgi structure. Part of a larger oligomeric complex. Interacts with p115. Interacts with RAB1B that has been activated by GTP-binding. Interacts with GORASP1/GRASP65 and ZFPL1. Belongs to the GOLGA2 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cytoskeletal Chromosomal Location of Human Ortholog: 9q34.11 Cellular Component: Golgi membrane; Golgi apparatus; cis-Golgi network; ER to Golgi transport vesicle; nucleus Molecular Function:protein binding; syntaxin binding; protein kinase binding Biological Process: mitotic cell cycle; negative regulation of protein binding |
| NCBI Summary: | The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This encoded protein has been postulated to play roles in the stacking of Golgi cisternae and in vesicular transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Feb 2010] |
| UniProt Code: | Q08379 |
| NCBI GenInfo Identifier: | 294862511 |
| NCBI Gene ID: | 2801 |
| NCBI Accession: | Q08379.3 |
| UniProt Secondary Accession: | Q08379,Q6GRM9, Q9BRB0, Q9NYF9, |
| UniProt Related Accession: | Q08379 |
| Molecular Weight: | 1002 |
| NCBI Full Name: | Golgin subfamily A member 2 |
| NCBI Synonym Full Names: | golgin A2 |
| NCBI Official Symbol: | GOLGA2 |
| NCBI Official Synonym Symbols: | GM130 |
| NCBI Protein Information: | Golgin subfamily A member 2; golgin-95; SY11 protein; GM130 autoantigen; Golgi matrix protein GM130; 130 kDa cis-Golgi matrix protein; golgi autoantigen, golgin subfamily a, 2 |
| UniProt Protein Name: | Golgin subfamily A member 2 |
| UniProt Synonym Protein Names: | 130 kDa cis-Golgi matrix protein; GM130; GM130 autoantigen; Golgin-95 |
| Protein Family: | Golgin subfamily |
| UniProt Gene Name: | GOLGA2 |
| UniProt Entry Name: | GOGA2_HUMAN |
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