Anti-Glucokinase Antibody (CAB5170)
- SKU:
- CAB5170
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
| Antibody Name: | Anti-Glucokinase Antibody |
| Antibody SKU: | CAB5170 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Glucokinase |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, Mouse liver, Rat liver |
| Immunogen: | A synthesized peptide derived from human Glucokinase |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 2645 |
| Uniprot: | P35557 |
| Cellular Location: | |
| Calculated MW: | 52kDa |
| Observed MW: | 52KDa |
| Synonyms: | FGQTL3, GK, GLK, HHF3, HK4, HKIV, HXKP, LGLK, MODY2 |
| Background: | Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI). [provided by RefSeq, Apr 2009] |
| UniProt Code: | P35557 |
| NCBI GenInfo Identifier: | 547696 |
| NCBI Gene ID: | 2645 |
| NCBI Accession: | P35557.1 |
| UniProt Secondary Accession: | P35557,Q05810, A4D2J2, A4D2J3, |
| UniProt Related Accession: | P35557 |
| Molecular Weight: | 465 |
| NCBI Full Name: | Glucokinase |
| NCBI Synonym Full Names: | glucokinase (hexokinase 4) |
| NCBI Official Symbol: | GCK |
| NCBI Official Synonym Symbols: | GK; GLK; HK4; HHF3; HKIV; HXKP; LGLK; MODY2; FGQTL3 |
| NCBI Protein Information: | glucokinase; HK IV; hexokinase-4; hexokinase-D; hexokinase type IV; hexokinase D, pancreatic isozyme; ATP:D-hexose 6-phosphotransferase |
| UniProt Protein Name: | Glucokinase |
| UniProt Synonym Protein Names: | Hexokinase type IV; HK IV; Hexokinase-4; HK4; Hexokinase-D |
| UniProt Gene Name: | GCK |
| UniProt Entry Name: | HXK4_HUMAN |
 | Western blot - Glucokinase Rabbit mAb (CAB5170) |
Related Products
Human GCK / Glucokinase ELISA Kit
Mouse GCK / Glucokinase ELISA Kit
