Anti-GGPS1 Antibody (CAB16233)
- SKU:
- CAB16233
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
| Antibody Name: | Anti-GGPS1 Antibody |
| Antibody SKU: | CAB16233 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GGPS1 (NP_001032354.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human GGPS1 (NP_001032354.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MEKT QETV QRIL LEPY KYLL QLPG KQVR TKLS QAFN HWLK VPED KLQI IIEV TEML HNAS LLID DIED NSKL RRGF PVAH SIYG IPSV INSA NYVY FLGL EKVL TLDH PDAV KLFT RQLL ELHQ GQGL DIYW RDNY TCPT EEEY KAMV LQKT GGLF GLAV GLMQ LFSD YKED LKPL LNTL GLFF QIRD DYAN LHSK EYSE NKSF CEDL TEGK FSFP TIHA IWSR PEST QVQN ILRQ RTEN IDIK KYCV HYLE DVGS FEYT RNTL KELE AKAY KQID ARGG NPEL VALV KHLS KMFK EENE |
| Gene ID: | 9453 |
| Uniprot: | O95749 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 28kDa/34kDa |
| Observed MW: | 32kDa |
| Synonyms: | GGPS1, GGPPS, GGPPS1 |
| Background: | This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, both protein-coding and non-protein-coding, have been found for this gene. |
| UniProt Protein Function: | GGPS1: Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins. Belongs to the FPP/GGPP synthase family. |
| UniProt Protein Details: | Protein type:Transferase; Secondary Metabolites Metabolism - terpenoid backbone biosynthesis; EC 2.5.1.10; EC 2.5.1.29; Motility/polarity/chemotaxis; EC 2.5.1.1 Chromosomal Location of Human Ortholog: 1q43 Cellular Component: cytosol Molecular Function:geranyltranstransferase activity; dimethylallyltranstransferase activity; farnesyltranstransferase activity; metal ion binding Biological Process: isoprenoid metabolic process; geranylgeranyl diphosphate biosynthetic process; geranyl diphosphate biosynthetic process; farnesyl diphosphate biosynthetic process; cholesterol biosynthetic process |
| NCBI Summary: | This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, both protein-coding and non-protein-coding, have been found for this gene. [provided by RefSeq, Sep 2010] |
| UniProt Code: | O95749 |
| NCBI GenInfo Identifier: | 6831549 |
| NCBI Gene ID: | 9453 |
| NCBI Accession: | O95749.1 |
| UniProt Related Accession: | O95749 |
| Molecular Weight: | 28kDa; 34kDa |
| NCBI Full Name: | Geranylgeranyl pyrophosphate synthase |
| NCBI Synonym Full Names: | geranylgeranyl diphosphate synthase 1 |
| NCBI Official Symbol: | GGPS1 |
| NCBI Official Synonym Symbols: | GGPPS; GGPPS1 |
| NCBI Protein Information: | geranylgeranyl pyrophosphate synthase |
| UniProt Protein Name: | Geranylgeranyl pyrophosphate synthase |
| UniProt Synonym Protein Names: | (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase (EC:2.5.1.1); Farnesyl diphosphate synthase; Farnesyltranstransferase (EC:2.5.1.29); Geranylgeranyl diphosphate synthase; Geranyltranstransferase (EC:2.5.1.10) |
| UniProt Gene Name: | GGPS1 |
| UniProt Entry Name: | GGPPS_HUMAN |
 | Western blot analysis of extracts of various cell lines, using GGPS1 antibody (CAB16233) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
Related Products
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
Human Anti-DSG3 antibody(anti-Desmoglein-3 antibody) ELISA Kit
