| Background: | This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | galectin-8: 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell adhesion Chromosomal Location of Human Ortholog: 1q43 Cellular Component: cytosol; extracellular space; membrane Molecular Function:carbohydrate binding; protein binding |
| NCBI Summary: | This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O00214 |
| NCBI GenInfo Identifier: | 292495094 |
| NCBI Gene ID: | 3964 |
| NCBI Accession: | O00214.4 |
| UniProt Secondary Accession: | O00214,O15215, Q5T3P5, Q5T3Q4, Q8TEV1, Q96B92, Q9BXC8 Q9H584, Q9H585, Q9UEZ6, Q9UP32, Q9UP33, |
| UniProt Related Accession: | O00214 |
| Molecular Weight: | 40,397 Da |
| NCBI Full Name: | Galectin-8 |
| NCBI Synonym Full Names: | galectin 8 |
| NCBI Official Symbol: | LGALS8 |
| NCBI Official Synonym Symbols: | Gal-8; PCTA1; PCTA-1; Po66-CBP |
| NCBI Protein Information: | galectin-8 |
| UniProt Protein Name: | Galectin-8 |
| UniProt Synonym Protein Names: | Po66 carbohydrate-binding protein; Po66-CBP; Prostate carcinoma tumor antigen 1; PCTA-1 |
| Protein Family: | Galectin |
| UniProt Gene Name: | LGALS8 |
| UniProt Entry Name: | LEG8_HUMAN |
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