Anti-Galectin 3 Antibody (CAB11198)
- SKU:
- CAB11198
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
| Antibody Name: | Anti-Galectin 3 Antibody |
| Antibody SKU: | CAB11198 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Galectin 3 |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HT-29, A-549, MCF7, RAW264.7, Mouse lung, Mouse spleen, Rat lung |
| Immunogen: | A synthesized peptide derived from human Galectin 3 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 3958 |
| Uniprot: | P17931 |
| Cellular Location: | |
| Calculated MW: | 30kDa |
| Observed MW: | 28KDa |
 | Western blot - Galectin 3 Rabbit mAb (CAB11198) |
| Synonyms: | CBP35, GAL3, GALBP, GALIG, L31, LGALS2, MAC2 |
| Background: | This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2014] |
| UniProt Protein Function: | Galectin-3: galactose-specific lectin which binds IgE. Expressed at a high level in the colonic epithelium. Also abundant in activated macrophages. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Extracellular matrix; Cell surface Chromosomal Location of Human Ortholog: 14q22.3 Cellular Component: spliceosome; extracellular matrix; extracellular space; proteinaceous extracellular matrix; membrane; mitochondrial inner membrane; cytoplasm; plasma membrane; immunological synapse; nucleus; external side of plasma membrane Molecular Function:protein binding; laminin binding; IgE binding; carbohydrate binding; chemoattractant activity Biological Process: neutrophil chemotaxis; extracellular matrix organization and biogenesis; RNA splicing; negative regulation of endocytosis; regulation of T cell proliferation; negative regulation of T cell receptor signaling pathway; macrophage chemotaxis; monocyte chemotaxis; epithelial cell differentiation; positive chemotaxis; eosinophil chemotaxis; innate immune response; mRNA processing; skeletal development |
| NCBI Summary: | This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2014] |
| UniProt Code: | P17931 |
| NCBI GenInfo Identifier: | 215274262 |
| NCBI Gene ID: | 3958 |
| NCBI Accession: | P17931.5 |
| UniProt Secondary Accession: | P17931,Q16005, Q6IBA7, Q96J47, B2RC38, |
| UniProt Related Accession: | P17931 |
| Molecular Weight: | |
| NCBI Full Name: | Galectin-3 |
| NCBI Synonym Full Names: | lectin, galactoside-binding, soluble, 3 |
| NCBI Official Symbol: | LGALS3 |
| NCBI Official Synonym Symbols: | L31; GAL3; MAC2; CBP35; GALBP; GALIG; LGALS2 |
| NCBI Protein Information: | galectin-3; lectin L-29; 35 kDa lectin; MAC-2 antigen; IgE-binding protein; laminin-binding protein; galactose-specific lectin 3; carbohydrate-binding protein 35 |
| UniProt Protein Name: | Galectin-3 |
| UniProt Synonym Protein Names: | 35 kDa lectin; Carbohydrate-binding protein 35; CBP 35; Galactose-specific lectin 3; Galactoside-binding protein; GALBP; IgE-binding protein; L-31; Laminin-binding protein; Lectin L-29; Mac-2 antigen |
| Protein Family: | Galectin |
| UniProt Gene Name: | LGALS3 |
| UniProt Entry Name: | LEG3_HUMAN |
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