Anti-FXR2 Antibody (CAB14092)
- SKU:
- CAB14092
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-FXR2 Antibody |
| Antibody SKU: | CAB14092 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 550-650 of human FXR2 (NP_004851.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | MCF7, U-251MG, PC-3, Mouse testis, Rat liver |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 550-650 of human FXR2 (NP_004851.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | RRRT DEDR TVMD GGLE SDGP NMTE NGLE DESR PQRR NRSR RRRN RGNR TDGS ISGD RQPV TVAD YISR AESQ SRQR PPLE RTKP SEDS LSGQ KGDS VSKL P |
| Gene ID: | 9513 |
| Uniprot: | P51116 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 74kDa |
| Observed MW: | 110kDa |
| Synonyms: | FXR2, FMR1L2, FXR2P |
| Background: | The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome. |
| UniProt Protein Function: | FXR2: RNA-binding protein. Interacts with FMR1 and FXR1. Interacts with CYFIP2 but not with CYFIP1. Interacts with TDRD3. Belongs to the FMR1 family. |
| UniProt Protein Details: | Protein type:RNA-binding Chromosomal Location of Human Ortholog: 17p13.1 Cellular Component: polysome; membrane; cytoplasm; nucleus Molecular Function:mRNA binding; identical protein binding; protein binding; RNA binding Biological Process: negative regulation of translation |
| NCBI Summary: | The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P51116 |
| NCBI GenInfo Identifier: | 90177782 |
| NCBI Gene ID: | 9513 |
| NCBI Accession: | P51116.2 |
| UniProt Secondary Accession: | P51116,Q86V09, Q8WUM2, B2R9M2, D3DTQ1, |
| UniProt Related Accession: | P51116 |
| Molecular Weight: | 673 |
| NCBI Full Name: | Fragile X mental retardation syndrome-related protein 2 |
| NCBI Synonym Full Names: | fragile X mental retardation, autosomal homolog 2 |
| NCBI Official Symbol: | FXR2 |
| NCBI Official Synonym Symbols: | FXR2P; FMR1L2 |
| NCBI Protein Information: | fragile X mental retardation syndrome-related protein 2; fragile X-mental retardation 1-like 2 |
| UniProt Protein Name: | Fragile X mental retardation syndrome-related protein 2 |
| Protein Family: | Fragile X mental retardation syndrome-related protein |
| UniProt Gene Name: | FXR2 |
| UniProt Entry Name: | FXR2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using FXR2 antibody (CAB14092) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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