Anti-FPR1 Antibody (CAB20455)
- SKU:
- CAB20455
- Product type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- FPR
- FMLP
Frequently bought together:
Description
| Product Name: | FPR1 Rabbit pAb |
| Product Code: | CAB20455 |
| Size: | 50uL, 100uL |
| Synonyms: | FPR, FMLP |
| Applications: | WB, IHC |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human FPR1. |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human |
| Immunogen: | Recombinant protein of human FPR1. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 2357 |
| Uniprot: | P21462 |
| Calculated MW: | 38kDa |
| Observed MW: | Refer to figures |
| UniProt Protein Function: | FPR1: High affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Protein type: Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Motility/polarity/chemotaxis; Receptor, GPCR Chromosomal Location of Human Ortholog: 19q13.4 Cellular Component: endosome; plasma membrane Molecular Function: N-formyl peptide receptor activity; protein binding; receptor activity Biological Process: activation of MAPK activity; cell motility; G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); nitric oxide mediated signal transduction; signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.[provided by RefSeq, Jul 2010] |
| UniProt Code: | P21462 |
| NCBI GenInfo Identifier: | 288558848 |
| NCBI Gene ID: | 2357 |
| NCBI Accession: | P21462.3 |
| UniProt Secondary Accession: | P21462,Q14939, Q7Z6A4, Q86U52, Q9NS48 |
| UniProt Related Accession: | P21462 |
| Molecular Weight: | 38,446 Da |
| NCBI Full Name: | fMet-Leu-Phe receptor |
| NCBI Synonym Full Names: | formyl peptide receptor 1 |
| NCBI Official Symbol: | FPR1 |
| NCBI Official Synonym Symbols: | FPR; FMLP |
| NCBI Protein Information: | fMet-Leu-Phe receptor |
| UniProt Protein Name: | fMet-Leu-Phe receptor |
| UniProt Synonym Protein Names: | N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor |
| Protein Family: | FK506-binding protein |
| UniProt Gene Name: | FPR1 |
| UniProt Entry Name: | FPR1_HUMAN |
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