Anti-FMN1 Antibody (CAB13143)
- SKU:
- CAB13143
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-FMN1 Antibody |
| Antibody SKU: | CAB13143 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 350-495 of human FMN1 (NP_001096654.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | 293T, A-549, U-87MG, LO2, Mouse testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 350-495 of human FMN1 (NP_001096654.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | NIDM PKTE PKGA DPES PRRE EMGC NADQ ESQS GPGV PQTQ GGEV KPKS PETA LEAF KALF IRPP RKGT TADT SELE ALKR KMRH EKES LRAV FERS NSKP ADGP SDSK SPDH SLTE QDDR TPGR LQAV WPPP KTKD TEEK VGLK YT |
| Gene ID: | 342184 |
| Uniprot: | Q68DA7 |
| Cellular Location: | Cell junction, Cell membrane, Cytoplasm, Cytoplasmic side, Nucleus, Peripheral membrane protein, adherens junction |
| Calculated MW: | 53kDa/71kDa/132kDa/157kDa |
| Observed MW: | 158kDa |
| Synonyms: | FMN1, FMN, LD, formin-1 |
| Background: | This gene belongs to the formin homology family and encodes a protein that has a role in the formation of adherens junction and the polymerization of linear actin cables. The homologous gene in mouse is associated with limb deformity. Alternatively spliced transcript variants have been found for this gene. |
| UniProt Protein Function: | FMN1: Plays a role in the formation of adherens junction and the polymerization of linear actin cables. Belongs to the formin homology family. Cappuccino subfamily. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; DNA-binding; Cell adhesion Chromosomal Location of Human Ortholog: 15q13.3 |
| NCBI Summary: | This gene belongs to the formin homology family and encodes a protein that has a role in the formation of adherens junction and the polymerization of linear actin cables. The homologous gene in mouse is associated with limb deformity. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015] |
| UniProt Code: | Q68DA7 |
| NCBI GenInfo Identifier: | 327478585 |
| NCBI Gene ID: | 342184 |
| NCBI Accession: | Q68DA7.3 |
| UniProt Secondary Accession: | Q68DA7,Q3B7I6, Q3ZAR4, Q6ZSY1, |
| UniProt Related Accession: | Q68DA7 |
| Molecular Weight: | 132,156 Da |
| NCBI Full Name: | Formin-1 |
| NCBI Synonym Full Names: | formin 1 |
| NCBI Official Symbol: | FMN1 |
| NCBI Official Synonym Symbols: | LD; FMN |
| NCBI Protein Information: | formin-1 |
| UniProt Protein Name: | Formin-1 |
| UniProt Synonym Protein Names: | Limb deformity protein homolog |
| Protein Family: | Formin |
| UniProt Gene Name: | FMN1 |
| UniProt Entry Name: | FMN1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using FMN1 antibody (CAB13143) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 1s. |
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