Anti-FIBP Antibody (CAB19908)[KO Validated]

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SKU:
CAB19908
Product type:
Antibody
Reactivity:
Human
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Frequently bought together:

Description

system_update_alt데이터시트system_update_alt안전 데이터시트
Antibody Name:Anti-FIBP Antibody [KO Validated]
Antibody SKU:CAB19908
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Rat
Host Species:Rabbit
Immunogen:Recombinant protein of human FIBP.
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Rat
Positive Samples:HeLa
Immunogen:Recombinant protein of human FIBP.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:9158
Uniprot:O43427
Cellular Location:Endomembrane system, Nucleus, Peripheral membrane protein
Calculated MW:41kDa
Observed MW:43KDa
Anti-FIBP Antibody [KO Validated] (CAB19908)Western blot analysis of extracts from normal (control) and FIBP knockout (KO) HeLa cells, using FIBP antibody (CAB19908) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.
Synonyms:FIBP, FGFIBP, FIBP-1, TROFAS
Background:Acidic fibroblast growth factor is mitogenic for a variety of different cell types and acts by stimulating mitogenesis or inducing morphological changes and differentiation. The FIBP protein is an intracellular protein that binds selectively to acidic fibroblast growth factor (aFGF). It is postulated that FIBP may be involved in the mitogenic action of aFGF. Two transcript variants encoding different isoforms have been found for this gene.
UniProt Protein Function:FIBP: May be involved in mitogenic function of FGF1. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 11q13.1

Cellular Component: nucleoplasm; membrane; mitochondrion; endomembrane system; nucleus

Molecular Function:fibroblast growth factor binding

Biological Process: fibroblast growth factor receptor signaling pathway

NCBI Summary:Acidic fibroblast growth factor is mitogenic for a variety of different cell types and acts by stimulating mitogenesis or inducing morphological changes and differentiation. The FIBP protein is an intracellular protein that binds selectively to acidic fibroblast growth factor (aFGF). It is postulated that FIBP may be involved in the mitogenic action of aFGF. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:O43427
NCBI GenInfo Identifier:13431517
NCBI Gene ID:9158
NCBI Accession:O43427.3
UniProt Secondary Accession:O43427,Q27Q85, Q6IBQ3, Q9HD65, A8K0J7,
UniProt Related Accession:O43427
Molecular Weight:364
NCBI Full Name:Acidic fibroblast growth factor intracellular-binding protein
NCBI Synonym Full Names:fibroblast growth factor (acidic) intracellular binding protein
NCBI Official Symbol:FIBP  
NCBI Official Synonym Symbols:FGFIBP; FIBP-1  
NCBI Protein Information:acidic fibroblast growth factor intracellular-binding protein; aFGF intracellular-binding protein; FGF-1 intracellular-binding protein
UniProt Protein Name:Acidic fibroblast growth factor intracellular-binding protein
UniProt Synonym Protein Names:FGF-1 intracellular-binding protein
Protein Family:Acidic fibroblast growth factor intracellular-binding protein
UniProt Gene Name:FIBP  
UniProt Entry Name:FIBP_HUMAN

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