Anti-FGF7/KGF Antibody (CAB5966)

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SKU:
CAB5966
Product type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
HBGF-7
KGF
Frequently bought together:

Description

Product Name:FGF7/KGF Rabbit mAb
Product Code:CAB5966
Size:20uL, 50uL, 100uL
Synonyms:HBGF-7, KGF
Applications:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human FGF7/FGF7/KGF
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:HeLa, A-549, Raji, Mouse lung, Mouse spleen, Mouse uterus, Rat lung, Rat spleen, Rat uterus
Immunogen:A synthesized peptide derived from human FGF7/FGF7/KGF
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:2252
Uniprot:P21781
Calculated MW:28kDa
Observed MW:23KDa
UniProt Protein Function:FGF7: Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation. Belongs to the heparin-binding growth factors family.
UniProt Protein Details:

Protein type:Secreted, signal peptide; Secreted; Cytokine

Chromosomal Location of Human Ortholog: 15q21.2

Cellular Component: Golgi apparatus; extracellular region

Molecular Function:heparin binding; protein binding; growth factor activity; fibroblast growth factor receptor binding; chemoattractant activity

Biological Process: epidermal growth factor receptor signaling pathway; positive regulation of keratinocyte migration; epidermis development; fibroblast growth factor receptor signaling pathway; hair follicle morphogenesis; phosphoinositide-mediated signaling; nerve growth factor receptor signaling pathway; mesenchymal cell proliferation; signal transduction; positive regulation of peptidyl-tyrosine phosphorylation; positive chemotaxis; positive regulation of cell division; positive regulation of cell proliferation; actin cytoskeleton reorganization; insulin receptor signaling pathway; response to wounding; innate immune response; positive regulation of epithelial cell proliferation

NCBI Summary:The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis. [provided by RefSeq, Jul 2008]
UniProt Code:P21781
NCBI GenInfo Identifier:122756
NCBI Gene ID:2252
NCBI Accession:P21781.1
UniProt Secondary Accession:P21781,Q6FGV5, Q96FG5, H0YNY5,
UniProt Related Accession:P21781
Molecular Weight:11,520 Da
NCBI Full Name:Fibroblast growth factor 7
NCBI Synonym Full Names:fibroblast growth factor 7
NCBI Official Symbol:FGF7  
NCBI Official Synonym Symbols:KGF; HBGF-7  
NCBI Protein Information:fibroblast growth factor 7; FGF-7; keratinocyte growth factor; heparin-binding growth factor 7
UniProt Protein Name:Fibroblast growth factor 7
UniProt Synonym Protein Names:Heparin-binding growth factor 7; HBGF-7; Keratinocyte growth factor
UniProt Gene Name:FGF7  
UniProt Entry Name:FGF7_HUMAN

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