Anti-Fetuin A/AHSG Antibody (CAB19264)
- SKU:
- CAB19264
- Product type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- AHSG
- A2HS
- AHS
- FETUA
- HSGA
- alpha-2-HS-glycoprotein
Frequently bought together:
Description
| Product Name: | Fetuin A/AHSG Rabbit mAb |
| Product Code: | CAB19264 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | AHSG, A2HS, AHS, FETUA, HSGA, alpha-2-HS-glycoprotein |
| Applications: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human Fetuin A/AHSG. |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | Human plasma |
| Immunogen: | Recombinant protein of human Fetuin A/AHSG. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 197 |
| Uniprot: | P02765 |
| Cellular Location: | Secreted |
| Calculated MW: | 58kDa |
| Observed MW: | 50KDa |
| UniProt Protein Function: | FETUA: Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions. Alpha-2-HS glycoprotein derives from this precursor, when the connecting peptide is cleaved off. The two chains A and B are held together by a single disulfide bond. Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins. Belongs to the fetuin family. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 3q27 Cellular Component: extracellular space; extracellular region Molecular Function:kinase inhibitor activity; cysteine protease inhibitor activity Biological Process: negative regulation of bone mineralization; pinocytosis; ossification; positive regulation of phagocytosis; regulation of inflammatory response; acute-phase response; negative regulation of phosphorylation; negative regulation of insulin receptor signaling pathway; skeletal development; regulation of bone mineralization |
| NCBI Summary: | Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P02765 |
| NCBI GenInfo Identifier: | 112910 |
| NCBI Gene ID: | 197 |
| NCBI Accession: | P02765.1 |
| UniProt Secondary Accession: | P02765,O14961, O14962, Q9P152, A8K9N6, B2R7G1, |
| UniProt Related Accession: | P02765,AAB29984 |
| Molecular Weight: | 39,325 Da |
| NCBI Full Name: | Alpha-2-HS-glycoprotein |
| NCBI Synonym Full Names: | alpha-2-HS-glycoprotein |
| NCBI Official Symbol: | AHSG |
| NCBI Official Synonym Symbols: | AHS; A2HS; HSGA; FETUA |
| NCBI Protein Information: | alpha-2-HS-glycoprotein; fetuin-A; alpha-2-Z-globulin; ba-alpha-2-glycoprotein |
| UniProt Protein Name: | Alpha-2-HS-glycoprotein |
| UniProt Synonym Protein Names: | Alpha-2-Z-globulin; Ba-alpha-2-glycoprotein; Fetuin-ACleaved into the following 2 chains:Alpha-2-HS-glycoprotein chain A; Alpha-2-HS-glycoprotein chain B |
| Protein Family: | Alpha-2-HS-glycoprotein |
| UniProt Gene Name: | AHSG |
| UniProt Entry Name: | FETUA_HUMAN |
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