Anti-FBXO10 Antibody (CAB14871)
- SKU:
- CAB14871
- Product type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
| Antibody Name: | Anti-FBXO10 Antibody |
| Antibody SKU: | CAB14871 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human FBXO10 (NP_036298.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Rat |
| Positive Samples: | Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human FBXO10 (NP_036298.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MEAG GLPL ELWR MILA YLHL PDLG RCSL VCRA WYEL ILSL DSTR WRQL CLGC TECR HPNW PNQP DVEP ESWR EAFK QHYL ASKT WTKN ALDL ESSI CFSL FRRR RERR TLSV GPGR EFDS LGSA LAMA SLYD RIVL FPGV YEEQ GEII LKVP VEIV GQGK LGEV ALLA SIDQ HCST TRLC |
| Gene ID: | 26267 |
| Uniprot: | Q9UK96 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 52kDa/105kDa |
| Observed MW: | 105kDa |
| Synonyms: | FBXO10, FBX10, PRMT11 |
| Background: |
| UniProt Protein Function: | PRMT11: Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. |
| UniProt Protein Details: | Protein type:Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 9p13.2 Cellular Component: cytoplasm; ubiquitin ligase complex Molecular Function:protein binding; ubiquitin-protein ligase activity Biological Process: regulation of apoptosis; apoptosis; protein ubiquitination during ubiquitin-dependent protein catabolic process; protein ubiquitination |
| NCBI Summary: | Members of the F-box protein family, such as FBXO10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9UK96 |
| NCBI GenInfo Identifier: | 124244083 |
| NCBI Gene ID: | 26267 |
| NCBI Accession: | NP_036298.2 |
| UniProt Secondary Accession: | Q9UK96,Q08AL3, Q5JRT8, Q9UKC3, |
| UniProt Related Accession: | Q9UK96 |
| Molecular Weight: | 105,195 Da |
| NCBI Full Name: | F-box only protein 10 |
| NCBI Synonym Full Names: | F-box protein 10 |
| NCBI Official Symbol: | FBXO10 |
| NCBI Official Synonym Symbols: | FBX10; PRMT11 |
| NCBI Protein Information: | F-box only protein 10; F-box protein Fbx10 |
| UniProt Protein Name: | F-box only protein 10 |
| Protein Family: | F-box only protein |
| UniProt Gene Name: | FBXO10 |
| UniProt Entry Name: | FBX10_HUMAN |
 | Western blot analysis of extracts of rat brain, using FBXO10 antibody (CAB14871) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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