Anti-FAM3B Antibody (CAB13592)
- SKU:
- CAB13592
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
| Antibody Name: | Anti-FAM3B Antibody |
| Antibody SKU: | CAB13592 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-235 of human FAM3B (NP_478066.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | 293T, Mouse intestine |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-235 of human FAM3B (NP_478066.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | ELIP DAPL SSAA YSIR SIGE RPVL KAPV PKRQ KCDH WTPC PSDT YAYR LLSG GGRS KYAK ICFE DNLL MGEQ LGNV ARGI NIAI VNYV TGNV TATR CFDM YEGD NSGP MTKF IQSA APKS LLFM VTYD DGST RLNN DAKN AIEA LGSK EIRN MKFR SSWV FIAA KGLE LPSE IQRE KINH SDAK NNRY SGWP AEIQ IEGC IPKE RS |
| Gene ID: | 54097 |
| Uniprot: | P58499 |
| Cellular Location: | Secreted |
| Calculated MW: | 20kDa/25kDa/30kDa |
| Observed MW: | 28kDa |
| Synonyms: | FAM3B, 2-21, C21orf11, C21orf76, ORF9, PANDER, PRED44 |
| Background: |
| UniProt Protein Function: | FAM3B: Induces apoptosis of alpha and beta cells in a dose- and time-dependent manner. Present in insulin secretory granules and likely cosecreted with insulin. Belongs to the FAM3 family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cytokine; Secreted; Apoptosis; Secreted, signal peptide; Nuclear envelope Chromosomal Location of Human Ortholog: 21q22.3 Cellular Component: extracellular space; extracellular region Molecular Function:cytokine activity Biological Process: insulin secretion; apoptosis |
| UniProt Code: | P58499 |
| NCBI GenInfo Identifier: | 23821535 |
| NCBI Gene ID: | 54097 |
| NCBI Accession: | P58499.2 |
| UniProt Related Accession: | P58499 |
| Molecular Weight: | 235 |
| NCBI Full Name: | Protein FAM3B |
| NCBI Synonym Full Names: | family with sequence similarity 3, member B |
| NCBI Official Symbol: | FAM3B |
| NCBI Official Synonym Symbols: | 2-21; ORF9; PANDER; PRED44; C21orf11; C21orf76 |
| NCBI Protein Information: | protein FAM3B; D21M16SJHU19e; pancreatic derived factor; pancreatic-derived factor; cytokine-like protein 2-21 |
| UniProt Protein Name: | Protein FAM3B |
| UniProt Synonym Protein Names: | Cytokine-like protein 2-21; Pancreatic-derived factor; PANDER |
| Protein Family: | Protein |
| UniProt Gene Name: | FAM3B |
| UniProt Entry Name: | FAM3B_HUMAN |
 | Western blot analysis of extracts of various cell lines, using FAM3B antibody (CAB13592) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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