Anti-FADS1 Antibody (CAB0178)
- SKU:
- CAB0178
- Product type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- FADS1
- D5D
- FADS6
- FADSD5
- LLCDL1
- TU12
- fatty acid desaturase 1
Frequently bought together:
Description
| Product Name: | FADS1 Rabbit mAb |
| Product Code: | CAB0178 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | FADS1, D5D, FADS6, FADSD5, LLCDL1, TU12, fatty acid desaturase 1 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human FADS1. |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, Mouse liver, Rat lung, Rat liver, Rat brain |
| Immunogen: | A synthesized peptide derived from human FADS1. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 3992 |
| Uniprot: | O60427 |
| Calculated MW: | 52kDa |
| Observed MW: | 52KDa |
| UniProt Protein Function: | FADS1: Component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3). Catalyzes the desaturation of dihomo-gamma-linoleic acid (DHGLA) (20:3n-6) and eicosatetraenoic acid (20:4n-3) to generate arachidonic acid (AA) (20:4n-6) and eicosapentaenoic acid (EPA)(20:5n-3) respectively. Belongs to the fatty acid desaturase family. |
| UniProt Protein Details: | Protein type:EC 1.14.19.-; Lipid Metabolism - unsaturated fatty acid biosynthesis; Membrane protein, integral; Membrane protein, multi-pass; Oxidoreductase Chromosomal Location of Human Ortholog: 11q12.2 Cellular Component: endoplasmic reticulum membrane; membrane Molecular Function:C-5 sterol desaturase activity; omega-6 fatty acid desaturase activity; oxidoreductase activity Biological Process: cellular response to starvation; icosanoid biosynthetic process; linoleic acid metabolic process; phospholipid biosynthetic process; unsaturated fatty acid biosynthetic process |
| NCBI Summary: | The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O60427 |
| NCBI GenInfo Identifier: | 565683215 |
| NCBI Gene ID: | 3992 |
| NCBI Accession: | O60427.3 |
| UniProt Secondary Accession: | O60427,Q53GM5, Q8N3A6, Q8NCC7, Q8NCG0, Q96I39, Q96SV3 Q96T10, Q9NRP8, Q9NYX1, A8K0I7, B2RAI0, |
| UniProt Related Accession: | O60427 |
| Molecular Weight: | 42,474 Da |
| NCBI Full Name: | Fatty acid desaturase 1 |
| NCBI Synonym Full Names: | fatty acid desaturase 1 |
| NCBI Official Symbol: | FADS1 |
| NCBI Official Synonym Symbols: | D5D; TU12; FADS6; FADSD5; LLCDL1 |
| NCBI Protein Information: | fatty acid desaturase 1 |
| UniProt Protein Name: | Fatty acid desaturase 1 |
| UniProt Synonym Protein Names: | Delta(5) fatty acid desaturase; D5D; Delta(5) desaturase; Delta-5 desaturase |
| Protein Family: | Fatty acid desaturase |
| UniProt Gene Name: | FADS1 |
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