Anti-EXOC3 Antibody (CAB17635)
- SKU:
- CAB17635
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-EXOC3 Antibody |
| Antibody SKU: | CAB17635 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 396-745 of human EXOC3 (NP_009208.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | PC-3, U-251MG, Mouse brain, Mouse lung, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 396-745 of human EXOC3 (NP_009208.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | RKAL ETDK KDWV KETE PEAD QDGY YQTT LPAI VFQM FEQN LQVA AQIS EDLK TKVL VLCL QQMN SFLS RYKD EAQL YKEE HLRN RQHP HCYV QYMI AIIN NCQT FKES IVSL KRKY LKNE VEEG VSPS QPSM DGIL DAIA KEGC SGLL EEVF LDLE QHLN ELMT KKWL LGSN AVDI ICVT VEDY FNDF AKIK KPYK KRMT AEAH RRVV VEYL RAVM QKRI SFRS PEER KEGA EKMV REAE QLRF LFRK LASG FGED VDGY CDTI VAVA EVIK LTDP SLLY LEVS TLVS KYPD IRDD HIGA LLAV RGDA SRDM KQTI METL EQGP AQAS PSYV PLFK DIVV PSLN VAKL LK |
| Gene ID: | 11336 |
| Uniprot: | O60645 |
| Cellular Location: | |
| Calculated MW: | 73kDa/85kDa/86kDa |
| Observed MW: | 87kDa |
 | Western blot - EXOC3 Rabbit pAb (CAB17635) |
| Synonyms: | EXOC3, SEC6, SEC6L1, Sec6p, EXOC3 |
| Background: | The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | SEC6L1: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC6 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Vesicle Chromosomal Location of Human Ortholog: 5p15.33 Cellular Component: cytosol; exocyst; secretory granule membrane Molecular Function:protein binding; SNARE binding Biological Process: exocyst localization; exocytosis |
| NCBI Summary: | The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O60645 |
| NCBI GenInfo Identifier: | 24418663 |
| NCBI Gene ID: | 11336 |
| NCBI Accession: | O60645.2 |
| UniProt Secondary Accession: | O60645,Q6P2E8, Q8TEN6, Q8WUW0, Q96DI4, |
| UniProt Related Accession: | O60645 |
| Molecular Weight: | 85,567 Da |
| NCBI Full Name: | Exocyst complex component 3 |
| NCBI Synonym Full Names: | exocyst complex component 3 |
| NCBI Official Symbol: | EXOC3 |
| NCBI Official Synonym Symbols: | SEC6; Sec6p; SEC6L1 |
| NCBI Protein Information: | exocyst complex component 3 |
| UniProt Protein Name: | Exocyst complex component 3 |
| UniProt Synonym Protein Names: | Exocyst complex component Sec6 |
| Protein Family: | Exocyst complex component |
| UniProt Gene Name: | EXOC3 |
| UniProt Entry Name: | EXOC3_HUMAN |
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