Anti-ERMAP Antibody (CAB10425)
- SKU:
- CAB10425
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-ERMAP Antibody |
| Antibody SKU: | CAB10425 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-155 of human ERMAP (NP_061008.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | BT-474, A-549, K-562, Mouse liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-155 of human ERMAP (NP_061008.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | HAGD AGKF HVAL LGGT AELL CPLS LWPG TVPK EVRW LRSP FPQR SQAV HIFR DGKD QDED LMPE YKGR TVLV RDAQ EGSV TLQI LDVR LEDQ GSYR CLIQ VGNL SKED TVIL QVAA PSVG SLSP SA |
| Gene ID: | 114625 |
| Uniprot: | Q96PL5 |
| Cellular Location: | Cell membrane, Cytoplasm, Single-pass type I membrane protein |
| Calculated MW: | 52kDa |
| Observed MW: | 53kDa |
| Synonyms: | ERMAP, BTN5, PRO2801, RD, SC |
| Background: | The protein encoded by this gene is a cell surface transmembrane protein that may act as an erythroid cell receptor, possibly as a mediator of cell adhesion. Polymorphisms in this gene are responsible for the Scianna/Radin blood group system. Two transcript variants encoding the same protein have been found for this gene. |
| UniProt Protein Function: | ERMAP: Possible role as a cell-adhesion or receptor molecule of erythroid cells. Belongs to the immunoglobulin superfamily. BTN/MOG family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 1p34.2 Cellular Component: plasma membrane Disease: Blood Group--scianna System; Radin Blood Group Antigen |
| NCBI Summary: | The protein encoded by this gene is a cell surface transmembrane protein that may act as an erythroid cell receptor, possibly as a mediator of cell adhesion. Polymorphisms in this gene are responsible for the Scianna/Radin blood group system. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q96PL5 |
| NCBI GenInfo Identifier: | 74761033 |
| NCBI Gene ID: | 114625 |
| NCBI Accession: | Q96PL5.1 |
| UniProt Secondary Accession: | Q96PL5,Q5VV53, Q6DUE0, Q7Z3X0, Q8NCV8, Q8NCW2, Q8NCW3 Q96PL6, D3DPW8, |
| UniProt Related Accession: | Q96PL5 |
| Molecular Weight: | 52,605 Da |
| NCBI Full Name: | Erythroid membrane-associated protein |
| NCBI Synonym Full Names: | erythroblast membrane associated protein (Scianna blood group) |
| NCBI Official Symbol: | ERMAP |
| NCBI Official Synonym Symbols: | RD; SC; BTN5; PRO2801 |
| NCBI Protein Information: | erythroid membrane-associated protein |
| UniProt Protein Name: | Erythroid membrane-associated protein |
| UniProt Synonym Protein Names: | Radin blood group antigen; Scianna blood group antigen |
| Protein Family: | Erythroid membrane-associated protein |
| UniProt Gene Name: | ERMAP |
| UniProt Entry Name: | ERMAP_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ERMAP antibody (CAB10425) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. |
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