Anti-EPB41L3 Antibody (CAB12759)
- SKU:
- CAB12759
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
| Antibody Name: | Anti-EPB41L3 Antibody |
| Antibody SKU: | CAB12759 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 656-865 of human EPB41L3 (NP_001268463.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | U-87MG, Mouse kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 656-865 of human EPB41L3 (NP_001268463.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | GDAA AQPA FTGI KGKE GSAL TEGA KEEG GEEV AKAV LEQE ETAA ASRE RQEE QSAA IHIS ETLE QKPH FESS TVKT ETIS FGSV SPGG VKLE ISTK EVPV VHTE TKTI TYES SQVD PGTD LEPG VLMS AQTI TSET TSTT TTTH ITKT VKGG ISET RIEK RIVI TGDA DIDH DQAL AQAI KEAK EQHP DMSV TKVV VHKE TEIT PEDG ED |
| Gene ID: | 23136 |
| Uniprot: | Q9Y2J2 |
| Cellular Location: | Cell junction, Cell membrane, Cytoplasm, Cytoplasmic side, Peripheral membrane protein, cytoskeleton |
| Calculated MW: | 69kDa/96kDa/98kDa/120kDa |
| Observed MW: | 121kDa |
| Synonyms: | EPB41L3, 4.1B, DAL-1, DAL1 |
| Background: |
| UniProt Protein Function: | EPB41L3: a possible tumor suppressor protein that plays a role in cell adhesion and apoptosis. Critical growth regulator in the pathogenesis of meningiomas. Three alternatively spliced isoforms have been described. |
| UniProt Protein Details: | Protein type:Cytoskeletal; Motility/polarity/chemotaxis; Tumor suppressor Chromosomal Location of Human Ortholog: 18p11.31 Cellular Component: axolemma; cytoskeleton; cytosol; intercellular junction; paranode region of axon; plasma membrane Molecular Function:protein binding; structural constituent of cytoskeleton Biological Process: actomyosin structure organization and biogenesis; cortical cytoskeleton organization and biogenesis; cytoskeletal anchoring; myelin maintenance; neurite morphogenesis; paranodal junction assembly; regulation of cell shape |
| UniProt Code: | Q9Y2J2 |
| NCBI GenInfo Identifier: | 17433099 |
| NCBI Gene ID: | 23136 |
| NCBI Accession: | Q9Y2J2.2 |
| UniProt Secondary Accession: | Q9Y2J2,O95713, Q9BRP5, B7Z4I5, F5GX05, |
| UniProt Related Accession: | Q9Y2J2 |
| Molecular Weight: | 121kDa |
| NCBI Full Name: | Band 4.1-like protein 3 |
| NCBI Synonym Full Names: | erythrocyte membrane protein band 4.1 like 3 |
| NCBI Official Symbol: | EPB41L3 |
| NCBI Official Synonym Symbols: | 4.1B; DAL1; DAL-1 |
| NCBI Protein Information: | band 4.1-like protein 3 |
| UniProt Protein Name: | Band 4.1-like protein 3 |
| UniProt Synonym Protein Names: | 4.1B; Differentially expressed in adenocarcinoma of the lung protein 1; DAL-1 |
| Protein Family: | Band 4.1-like protein |
| UniProt Gene Name: | EPB41L3 |
 | Western blot analysis of extracts of various cell lines, using EPB41L3 antibody (CAB12759) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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