Anti-ENO1 Antibody (CAB16841)
- SKU:
- CAB16841
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
| Antibody Name: | Anti-ENO1 Antibody |
| Antibody SKU: | CAB16841 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-434 of human ENO1 (NP_001419.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-434 of human ENO1 (NP_001419.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSIL KIHA REIF DSRG NPTV EVDL FTSK GLFR AAVP SGAS TGIY EALE LRDN DKTR YMGK GVSK AVEH INKT IAPA LVSK KLNV TEQE KIDK LMIE MDGT ENKS KFGA NAIL GVSL AVCK AGAV EKGV PLYR HIAD LAGN SEVI LPVP AFNV INGG SHAG NKLA MQEF MILP VGAA NFRE AMRI GAEV YHNL KNVI KEKY GKDA TNVG DEGG FAPN ILEN KEGL ELLK TAIG KAGY TDKV VIGM DVAA SEFF RSGK YDLD FKSP DDPS RYIS PDQL ADLY KSFI KDYP VVSI EDPF DQDD WGAW QKFT ASAG IQVV GDDL TVTN PKRI AKAV NEKS CNCL LLKV NQIG SVTE SLQA CKLA QANG WGVM VSHR SGET EDTF IADL VVGL CTGQ IKTG APCR SERL AKYN QLLR IEEE LGSK AKFA GRNF RNPL AK |
| Gene ID: | 2023 |
| Uniprot: | P06733 |
| Cellular Location: | |
| Calculated MW: | 36kDa/47kDa |
| Observed MW: | Refer to figures |
 | Immunofluorescence - ENO1 Rabbit pAb (CAB16841) |
| Synonyms: | ENO1, ENO1L1, HEL-S-17, MPB1, NNE, PPH, enolase 1 |
| Background: | This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy. |
| UniProt Protein Function: | ENO1: an abundant cytoplasmic enzyme with 2-phospho-D-glycerate hydro-lyase activity. A target of excess protein nitration in Alzheimer disease (AD) brain. Tau-crystallin, a structural lens protein, is produced from an alternative translation start in the enolase gene. |
| UniProt Protein Details: | Protein type:Transcription, coactivator/corepressor; EC 4.2.1.11; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Lyase Chromosomal Location of Human Ortholog: 1p36.2 Cellular Component: cytoplasm; cytosol; extracellular space; M band; membrane; nucleus; phosphopyruvate hydratase complex; plasma membrane Molecular Function:DNA binding; GTPase binding; magnesium ion binding; phosphopyruvate hydratase activity; protein binding; transcription corepressor activity; transcription factor activity Biological Process: carbohydrate metabolic process; gluconeogenesis; glucose metabolic process; negative regulation of cell growth; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; response to virus; transcription, DNA-dependent |
| NCBI Summary: | This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy. [provided by RefSeq, Jan 2011] |
| UniProt Code: | P06733 |
| NCBI GenInfo Identifier: | 119339 |
| NCBI Gene ID: | 2023 |
| NCBI Accession: | P06733.2 |
| UniProt Secondary Accession: | P06733,P22712, Q16704, Q4TUS4, Q53FT9, Q53HR3, Q658M5 Q6GMP2, Q71V37, Q7Z3V6, Q8WU71, B2RD59, |
| UniProt Related Accession: | P06733 |
| Molecular Weight: | 36,928 Da |
| NCBI Full Name: | Alpha-enolase |
| NCBI Synonym Full Names: | enolase 1, (alpha) |
| NCBI Official Symbol: | ENO1 |
| NCBI Official Synonym Symbols: | NNE; PPH; MPB1; ENO1L1; HEL-S-17 |
| NCBI Protein Information: | alpha-enolase; c-myc promoter-binding protein-1 |
| UniProt Protein Name: | Alpha-enolase |
| UniProt Synonym Protein Names: | 2-phospho-D-glycerate hydro-lyase; C-myc promoter-binding protein; Enolase 1; MBP-1; MPB-1; Non-neural enolase; NNE; Phosphopyruvate hydratase; Plasminogen-binding protein |
| UniProt Gene Name: | ENO1 |
| UniProt Entry Name: | ENOA_HUMAN |
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