Anti-ELP5 Antibody (CAB14862)
- SKU:
- CAB14862
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| Antibody Name: | Anti-ELP5 Antibody |
| Antibody SKU: | CAB14862 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 17-316 of human ELP5 (NP_056177.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | U-251MG, LO2, A375, Mouse brain, Mouse skeletal muscle, Mouse testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 17-316 of human ELP5 (NP_056177.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MLDS LLAL GGLV LLRD SVEW EGRS LLKA LVKK SALC GEQV HILG CEVS EEEF REGF DSDI NNRL VYHD FFRD PLNW SKTE EAFP GGPL GALR AMCK RTDP VPVT IALD SLSW LLLR LPCT TLCQ VLHA VSHQ DSCP GDSS SVGK VSVL GLLH EELH GPGP VGAL SSLA QTEV TLGG TMGQ ASAH ILCR RPRQ RPTD QTQW FSIL PDFS LDLQ EGPS VESQ PYSD PHIP PVDP TTHL TFNL HLSK KERE ARDS LILP FQFS SEKQ QALL RPRP GQAT SHIF YEPD AYDD LDQE DPDD DLDI |
| Gene ID: | 23587 |
| Uniprot: | Q8TE02 |
| Cellular Location: | Cytoplasm, Nucleus |
| Calculated MW: | 19kDa/30kDa/34kDa/35kDa |
| Observed MW: | 38kDa |
| Synonyms: | ELP5, C17orf81, DERP6, HSPC002, MST071, MSTP071 |
| Background: |
| UniProt Protein Function: | Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in cell migration. May be involved in TP53-mediated transcriptional regulation. |
| UniProt Code: | Q8TE02 |
| NCBI GenInfo Identifier: | 44662830 |
| NCBI Gene ID: | 23587 |
| NCBI Accession: | NP_056177.3 |
| UniProt Secondary Accession: | Q8TE02,Q659B6, Q7Z2T4, Q8TDR9, Q9BUB2, Q9Y2Q4, A8K1M5 D3DTN9, |
| UniProt Related Accession: | Q8TE02 |
| Molecular Weight: | Calculated: 19kDa; 30kDa; 34kDa; 35kDaObserved: 38kDa |
| NCBI Full Name: | elongator complex protein 5 isoform 1 |
| NCBI Synonym Full Names: | elongator acetyltransferase complex subunit 5 |
| NCBI Official Symbol: | ELP5 |
| NCBI Official Synonym Symbols: | DERP6; MST071; HSPC002; MSTP071; C17orf81 |
| NCBI Protein Information: | elongator complex protein 5 |
| UniProt Protein Name: | Elongator complex protein 5 |
| UniProt Synonym Protein Names: | Dermal papilla-derived protein 6; S-phase 2 protein |
| Protein Family: | Elongator complex protein |
| UniProt Gene Name: | ELP5 |
 | Western blot analysis of extracts of various cell lines, using ELP5 antibody (CAB14862) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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