Anti-ELMOD2 Antibody (CAB14524)
- SKU:
- CAB14524
- Product type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
| Antibody Name: | Anti-ELMOD2 Antibody |
| Antibody SKU: | CAB14524 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 5-95 of human ELMOD2 (NP_714913.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Rat |
| Positive Samples: | Rat lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 5-95 of human ELMOD2 (NP_714913.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LWEF FYGH FFRF WMKW LLRQ MTGK CELQ RIFD TYVG AQRT HRIE NSLT YSKN KVLQ KATH VVQS EVDK YVDD IMKE KNIN PEKD ASFK ICM |
| Gene ID: | 255520 |
| Uniprot: | Q8IZ81 |
| Cellular Location: | |
| Calculated MW: | 34kDa |
| Observed MW: | 33kDa |
| Synonyms: | ELMOD2, 9830169G11Rik |
| Background: | This gene encodes one of six engulfment and motility (ELMO) domain-containing proteins. This gene is thought to play a role in antiviral responses. Mutations in this gene may be involved in the cause of familial idiopathic pulmonary fibrosis. |
| UniProt Protein Function: | ELMOD2: Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family. Regulates IFN-related antiviral responses. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 4q31.1 Cellular Component: membrane Molecular Function:GTPase activator activity Biological Process: regulation of defense response to virus Disease: Pulmonary Fibrosis, Idiopathic |
| NCBI Summary: | This gene encodes one of six engulfment and motility (ELMO) domain-containing proteins. This gene is thought to play a role in antiviral responses. Mutations in this gene may be involved in the cause of familial idiopathic pulmonary fibrosis. [provided by RefSeq, Sep 2010] |
| UniProt Code: | Q8IZ81 |
| NCBI GenInfo Identifier: | 74728441 |
| NCBI Gene ID: | 255520 |
| NCBI Accession: | Q8IZ81.1 |
| UniProt Secondary Accession: | Q8IZ81,B2R712, D3DNZ0, |
| UniProt Related Accession: | Q8IZ81 |
| Molecular Weight: | 34,961 Da |
| NCBI Full Name: | ELMO domain-containing protein 2 |
| NCBI Synonym Full Names: | ELMO domain containing 2 |
| NCBI Official Symbol: | ELMOD2 |
| NCBI Official Synonym Symbols: | 9830169G11Rik |
| NCBI Protein Information: | ELMO domain-containing protein 2 |
| UniProt Protein Name: | ELMO domain-containing protein 2 |
| Protein Family: | ELMO domain-containing protein |
| UniProt Gene Name: | ELMOD2 |
| UniProt Entry Name: | ELMD2_HUMAN |
 | Western blot analysis of extracts of rat lung, using ELMOD2 antibody (CAB14524) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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