Anti-EIF4E3 Antibody (CAB13879)
- SKU:
- CAB13879
- Product type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
| Antibody Name: | Anti-EIF4E3 Antibody |
| Antibody SKU: | CAB13879 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-118 of human EIF4E3 (NP_775495.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse lung, Rat lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-118 of human EIF4E3 (NP_775495.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MRGE RRPL WEEE SNAK GGVW KMKV PKDS TSTV WKEL LLAT IGEQ FTDC AAAD DEVI GVSV SVRD REDV VQVW NVNA SLVG EATV LEKI YELL PHIT FKAV FYKP HEEH HAFE GGRG KH |
| Gene ID: | 317649 |
| Uniprot: | Q8N5X7 |
| Cellular Location: | |
| Calculated MW: | 13kDa/24kDa |
| Observed MW: | 24kDa |
| Synonyms: | EIF4E3, eIF-4E3, eIF4E-3 |
| Background: |
| UniProt Protein Function: | Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis. May act as an inhibitor of EIF4E1 activity. |
| NCBI Summary: | EIF4E3 belongs to the EIF4E family of translational initiation factors that interact with the 5-prime cap structure of mRNA and recruit mRNA to the ribosome (Joshi et al., 2004 [PubMed 15153109]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q8N5X7 |
| NCBI GenInfo Identifier: | 197382649 |
| NCBI Gene ID: | 317649 |
| NCBI Accession: | NP_001128121.1 |
| UniProt Secondary Accession: | Q8N5X7,Q6NUT1, B2R963, |
| UniProt Related Accession: | Q8N5X7 |
| Molecular Weight: | Calculated: 13kDa; 24kDaObserved: 24kDa |
| NCBI Full Name: | eukaryotic translation initiation factor 4E type 3 isoform b |
| NCBI Synonym Full Names: | eukaryotic translation initiation factor 4E family member 3 |
| NCBI Official Symbol: | EIF4E3 |
| NCBI Official Synonym Symbols: | eIF-4E3; eIF4E-3 |
| NCBI Protein Information: | eukaryotic translation initiation factor 4E type 3 |
| UniProt Protein Name: | Eukaryotic translation initiation factor 4E type 3 |
| Protein Family: | Eukaryotic translation initiation factor |
| UniProt Gene Name: | EIF4E3 |
 | Western blot analysis of extracts of various cell lines, using EIF4E3 antibody (CAB13879) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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