Anti-DP1 Antibody (CAB5214)
- SKU:
- CAB5214
- Product type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| Antibody Name: | Anti-DP1 Antibody |
| Antibody SKU: | CAB5214 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human DP1 |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Rat |
| Positive Samples: | HeLa, RD, Raji |
| Immunogen: | A synthesized peptide derived from human DP1 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 7027 |
| Uniprot: | Q14186 |
| Cellular Location: | |
| Calculated MW: | 50kDa |
| Observed MW: | 50KDa |
| Synonyms: | DILC, DP1, DRTF1, Dp-1 |
| Background: | This gene encodes a member of a family of transcription factors that heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. The encoded protein functions as part of this complex to control the transcriptional activity of numerous genes involved in cell cycle progression from G1 to S phase. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1, 15, and X.[provided by RefSeq, Jan 2009] |
| UniProt Protein Function: | TFDP1: Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1/DP complex appears to mediate both cell proliferation and apoptosis. Belongs to the E2F/DP family. |
| UniProt Protein Details: | Protein type:Transcription, coactivator/corepressor; DNA-binding Chromosomal Location of Human Ortholog: 13q34 Cellular Component: nucleoplasm; nucleus Molecular Function:protein binding; protein domain specific binding; transcription factor activity; transcription factor binding Biological Process: cell proliferation; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter |
| NCBI Summary: | This gene encodes a member of a family of transcription factors that heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. The encoded protein functions as part of this complex to control the transcriptional activity of numerous genes involved in cell cycle progression from G1 to S phase. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1, 15, and X.[provided by RefSeq, Jan 2009] |
| UniProt Code: | Q14186 |
| NCBI GenInfo Identifier: | 3122926 |
| NCBI Gene ID: | 7027 |
| NCBI Accession: | Q14186.1 |
| UniProt Secondary Accession: | Q14186,Q5JSB4, Q8IZL5, B4DLQ9, |
| UniProt Related Accession: | Q14186 |
| Molecular Weight: | 34,921 Da |
| NCBI Full Name: | Transcription factor Dp-1 |
| NCBI Synonym Full Names: | transcription factor Dp-1 |
| NCBI Official Symbol: | TFDP1 |
| NCBI Official Synonym Symbols: | DP1; DILC; Dp-1; DRTF1 |
| NCBI Protein Information: | transcription factor Dp-1 |
| UniProt Protein Name: | Transcription factor Dp-1 |
| UniProt Synonym Protein Names: | DRTF1-polypeptide 1; DRTF1; E2F dimerization partner 1 |
| Protein Family: | Transcription factor |
| UniProt Gene Name: | TFDP1 |
| UniProt Entry Name: | TFDP1_HUMAN |
 | Western blot - DP1 Rabbit mAb (CAB5214) |
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