Anti-DENND4A Antibody (CAB16095)
- SKU:
- CAB16095
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| Antibody Name: | Anti-DENND4A Antibody |
| Antibody SKU: | CAB16095 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1500-1650 of human DENND4A (NP_005839.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | HepG2, mouse liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1500-1650 of human DENND4A (NP_005839.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | RPGR YFLK SSPS TENM HFPS SISS QTRQ SCIS TSAS GLDT SALS VQGN FDLN SKSK LQEN FCTR SIQI PANR SKTA MSKC PIFP MARS ISTS GPLD KEDT GRQK LIST GSLP ATLQ GATD SLGL EWHL PSPD PVTV PYLS PLVV WKEL ESL |
| Gene ID: | 10260 |
| Uniprot: | Q7Z401 |
| Cellular Location: | Nucleus |
| Calculated MW: | 209kDa/213kDa |
| Observed MW: | 209kDa |
| Synonyms: | DENND4A, IRLB, MYCPBP |
| Background: | This gene encodes a DENN domain-containing protein that may function as a guanine nucleotide exchange factor that specifically activates ras-related protein Rab-10. This protein also contains a interferon stimulated response element-binding domain and may be involved in regulating the v-myc avian myelocytomatosis viral (MYC) oncogene. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. |
| NCBI Summary: | This gene encodes a DENN domain-containing protein that may function as a guanine nucleotide exchange factor that specifically activates ras-related protein Rab-10. This protein also contains a interferon stimulated response element-binding domain and may be involved in regulating the v-myc avian myelocytomatosis viral (MYC) oncogene. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. [provided by RefSeq, Mar 2016] |
| UniProt Code: | Q7Z401 |
| NCBI GenInfo Identifier: | 221307566 |
| NCBI Gene ID: | 10260 |
| NCBI Accession: | NP_005839 |
| UniProt Related Accession: | Q7Z401 |
| Molecular Weight: | |
| NCBI Full Name: | C-myc promoter-binding protein isoform 2 |
| NCBI Synonym Full Names: | DENN domain containing 4A |
| NCBI Official Symbol: | DENND4A |
| NCBI Official Synonym Symbols: | IRLB; MYCPBP |
| NCBI Protein Information: | C-myc promoter-binding protein |
| UniProt Protein Name: | C-myc promoter-binding protein |
| UniProt Synonym Protein Names: | DENN domain-containing protein 4A |
| Protein Family: | Paralemmin |
| UniProt Gene Name: | DENND4A |
| UniProt Entry Name: | MYCPP_HUMAN |
 | Western blot analysis of extracts of various cell lines, using DENND4A antibody (CAB16095) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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