Anti-DEFB132 Antibody (CAB1074)
- SKU:
- CAB1074
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-DEFB132 Antibody |
| Antibody SKU: | CAB1074 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human DEFB132 (NP_997352.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse testis, Mouse liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human DEFB132 (NP_997352.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MKFL LLVL AALG FLTQ VIPA SAGG SKCV SNTP GYCR TCCH WGET ALFM CNAS RKCC ISYS FLPK PDLP QLIG NHWQ SRRR NTQR KDKK QQTT VTS |
| Gene ID: | 400830 |
| Uniprot: | Q7Z7B7 |
| Cellular Location: | Secreted |
| Calculated MW: | 10kDa |
| Observed MW: | 13kDa |
| Synonyms: | DEFB132, BD-32, DEFB-32, DEFB32, HEL-75, KFLL827, UNQ827 |
| Background: | Defensins are cysteine-rich cationic polypeptides that are important in the immunologic response to invading microorganisms. The protein encoded by this gene is secreted and is a member of the beta defensin protein family. This protein binds spermatozoa and has antimicrobial activity against E. coli. Beta defensin genes are found in several clusters throughout the genome, with this gene mapping to a cluster at 20p13. |
| UniProt Protein Function: | DEFB132: Has antibacterial activity (Potential). Belongs to the beta-defensin family. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 20p13 Cellular Component: cell surface; extracellular region Biological Process: defense response to bacterium; innate immune response |
| NCBI Summary: | Defensins are cysteine-rich cationic polypeptides that are important in the immunologic response to invading microorganisms. The protein encoded by this gene is secreted and is a member of the beta defensin protein family. This protein binds spermatozoa and has antimicrobial activity against E. coli. Beta defensin genes are found in several clusters throughout the genome, with this gene mapping to a cluster at 20p13. [provided by RefSeq, Nov 2014] |
| UniProt Code: | Q7Z7B7 |
| NCBI GenInfo Identifier: | 61212742 |
| NCBI Gene ID: | 400830 |
| NCBI Accession: | Q7Z7B7.1 |
| UniProt Related Accession: | Q7Z7B7 |
| Molecular Weight: | |
| NCBI Full Name: | Beta-defensin 132 |
| NCBI Synonym Full Names: | defensin beta 132 |
| NCBI Official Symbol: | DEFB132 |
| NCBI Official Synonym Symbols: | BD-32; DEFB32; HEL-75; UNQ827; DEFB-32; KFLL827 |
| NCBI Protein Information: | beta-defensin 132 |
| UniProt Protein Name: | Beta-defensin 132 |
| UniProt Synonym Protein Names: | Beta-defensin 32; BD-32; DEFB-32; Defensin HEL-75; Defensin, beta 132 |
| Protein Family: | Beta-defensin |
| UniProt Gene Name: | DEFB132 |
| UniProt Entry Name: | DB132_HUMAN |
 | Western blot analysis of extracts of various cell lines, using DEFB132 antibody (CAB1074) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. |
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