Anti-DECR1 Antibody (CAB13014)

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SKU:
CAB13014
Product type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism
Frequently bought together:

Description

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Antibody Name:Anti-DECR1 Antibody
Antibody SKU:CAB13014
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 35-335 of human DECR1 (NP_001350.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:HepG2, BxPC-3, 293T, A-549, Mouse brain, Mouse liver, Rat liver
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 35-335 of human DECR1 (NP_001350.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:NTEA LQSK FFSP LQKA MLPP NSFQ GKVA FITG GGTG LGKG MTTL LSSL GAQC VIAS RKMD VLKA TAEQ ISSQ TGNK VHAI QCDV RDPD MVQN TVSE LIKV AGHP NIVI NNAA GNFI SPTE RLSP NAWK TITD IVLN GTAF VTLE IGKQ LIKA QKGA AFLS ITTI YAET GSGF VVPS ASAK AGVE AMSK SLAA EWGK YGMR FNVI QPGP IKTK GAFS RLDP TGTF EKEM IGRI PCGR LGTV EELA NLAA FLCS DYAS WING AVIK FDGG EEVL ISGE FNDL RKVT KEQW DTIE ELIR KTKG S
Gene ID:1666
Uniprot:Q16698
Cellular Location:Mitochondrion
Calculated MW:34kDa/36kDa
Observed MW:34kDa
Synonyms:DECR1, DECR, NADPH, SDR18C1, 2
Background:This gene encodes an accessory enzyme which participates in the beta-oxidation and metabolism of unsaturated fatty enoyl-CoA esters.
UniProt Protein Function:DECR1: Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.
UniProt Protein Details:

Protein type:Oxidoreductase; EC 1.3.1.34; Mitochondrial

Chromosomal Location of Human Ortholog: 8q21.3

Cellular Component: cytoplasm; mitochondrial matrix; mitochondrion; nucleoplasm; nucleus

Molecular Function:2,4-dienoyl-CoA reductase (NADPH) activity; oxidoreductase activity, acting on NADH or NADPH

Biological Process: fatty acid beta-oxidation; protein homotetramerization

NCBI Summary:This gene encodes an accessory enzyme which participates in the beta-oxidation and metabolism of unsaturated fatty enoyl-CoA esters. [provided by RefSeq, Jul 2008]
UniProt Code:Q16698
NCBI GenInfo Identifier:3913456
NCBI Gene ID:1666
NCBI Accession:Q16698.1
UniProt Secondary Accession:Q16698,Q2M304, Q93085, B7Z6B8,
UniProt Related Accession:Q16698
Molecular Weight:
NCBI Full Name:2,4-dienoyl-CoA reductase, mitochondrial
NCBI Synonym Full Names:2,4-dienoyl-CoA reductase 1, mitochondrial
NCBI Official Symbol:DECR1  
NCBI Official Synonym Symbols:DECR; NADPH; SDR18C1  
NCBI Protein Information:2,4-dienoyl-CoA reductase, mitochondrial
UniProt Protein Name:2,4-dienoyl-CoA reductase, mitochondrial
UniProt Synonym Protein Names:2,4-dienoyl-CoA reductase [NADPH]; 4-enoyl-CoA reductase [NADPH]; Short chain dehydrogenase/reductase family 18C member 1
Protein Family:2,4-dienoyl-CoA reductase
UniProt Gene Name:DECR1  
UniProt Entry Name:DECR_HUMAN
Anti-DECR1 Antibody (CAB13014)Western blot analysis of extracts of various cell lines, using DECR1 antibody (CAB13014) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.

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