Anti-DCAF12 Antibody (CAB16510)
- SKU:
- CAB16510
- Product type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| Antibody Name: | Anti-DCAF12 Antibody |
| Antibody SKU: | CAB16510 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-85 of human DCAF12 (NP_056212.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Rat |
| Positive Samples: | HepG2, Rat kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-85 of human DCAF12 (NP_056212.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MARK VVSR KRKA PASP GAGS DAQG PQFG WDHS LHKR KRLP PVKR SLVY YLKN REVR LQNE TSYS RVLH GYAA QQLP SLLK EREF H |
| Gene ID: | 25853 |
| Uniprot: | Q5T6F0 |
| Cellular Location: | Cytoplasm, centrosome, cytoskeleton, microtubule organizing center |
| Calculated MW: | 50kDa |
| Observed MW: | 47kDa |
| Synonyms: | DCAF12, CT102, KIAA1892, TCC52, WDR40A |
| Background: | This gene encodes a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. |
| UniProt Protein Function: | WDR40A: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. Belongs to the WD repeat DCAF12 family. |
| UniProt Protein Details: | Protein type:Cancer Testis Antigen (CTA) Chromosomal Location of Human Ortholog: 9p13.3 Cellular Component: centrosome; cytoplasm Biological Process: protein ubiquitination |
| NCBI Summary: | This gene encodes a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. [provided by RefSeq, Jul 2009] |
| UniProt Code: | Q5T6F0 |
| NCBI GenInfo Identifier: | 74756352 |
| NCBI Gene ID: | 25853 |
| NCBI Accession: | Q5T6F0.1 |
| UniProt Secondary Accession: | Q5T6F0,Q5T6E9, Q5T6F1, Q6P3V0, Q7L4F8, Q96PZ5, Q9NXA9 Q9UFJ1, A8KA70, D3DRL6, |
| UniProt Related Accession: | Q5T6F0 |
| Molecular Weight: | 50,517 Da |
| NCBI Full Name: | DDB1- and CUL4-associated factor 12 |
| NCBI Synonym Full Names: | DDB1 and CUL4 associated factor 12 |
| NCBI Official Symbol: | DCAF12 |
| NCBI Official Synonym Symbols: | CT102; TCC52; WDR40A; KIAA1892 |
| NCBI Protein Information: | DDB1- and CUL4-associated factor 12 |
| UniProt Protein Name: | DDB1- and CUL4-associated factor 12 |
| UniProt Synonym Protein Names: | Centrosome-related protein TCC52; Testis cancer centrosome-related protein; WD repeat-containing protein 40A |
| Protein Family: | DDB1- and CUL4-associated factor |
| UniProt Gene Name: | DCAF12 |
| UniProt Entry Name: | DCA12_HUMAN |
 | Western blot analysis of extracts of various cell lines, using DCAF12 antibody (CAB16510) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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