Anti-DCAF11 Antibody (CAB15519)

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SKU:
CAB15519
Product type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
Frequently bought together:

Description

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Antibody Name:Anti-DCAF11 Antibody
Antibody SKU:CAB15519
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human DCAF11 (NP_079506.3).
Application:WB
Recommended Dilution:WB 1:200 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:LO2, HeLa, Mouse brain, Mouse heart, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human DCAF11 (NP_079506.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MGSR NSSS AGSG SGDP SEGL PRRG AGLR RSEE EEEE DEDV DLAQ VLAY LLRR GQVR LVQG GGAA NLQF IQAL LDSE EEND RAWD GRLG DRYN PPVD ATPD TREL EFNE IKTQ VELA TGQL GLRR AAQK HSFP RMLH QRER GLCH RGSF SLGE QSRV ISHF LPND LGFT DS
Gene ID:80344
Uniprot:Q8TEB1
Cellular Location:
Calculated MW:50kDa/58kDa/61kDa
Observed MW:61kDa
Synonyms:DCAF11, GL014, PRO2389, WDR23
Background:This gene encodes a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. Multiple alternatively spliced transcript variants have been found for this gene.
UniProt Protein Function:WDR23: a WD40 repeat protein. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. Three alternatively spliced human isoforms have been described.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: nucleoplasm

Molecular Function:protein binding

Biological Process: protein ubiquitination

NCBI Summary:This gene encodes a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2009]
UniProt Code:Q8TEB1
NCBI GenInfo Identifier:39644614
NCBI Gene ID:80344
NCBI Accession:AAH08858.2
UniProt Secondary Accession:Q8TEB1,Q5D039, Q86U00, Q86U39, Q8NDN2, Q9H2J0, Q9H3A3 Q9H5C9, B3KQ83, D3DS56,
UniProt Related Accession:Q8TEB1
Molecular Weight:62 kDa (MW of target protein)
NCBI Full Name:WDR23 protein, partial
NCBI Synonym Full Names:DDB1 and CUL4 associated factor 11
NCBI Official Symbol:DCAF11  
NCBI Official Synonym Symbols:GL014; WDR23; PRO2389  
NCBI Protein Information:DDB1- and CUL4-associated factor 11
UniProt Protein Name:DDB1- and CUL4-associated factor 11
UniProt Synonym Protein Names:WD repeat-containing protein 23
UniProt Gene Name:DCAF11  
UniProt Entry Name:DCA11_HUMAN
Anti-DCAF11 Antibody (CAB15519)Western blot analysis of extracts of various cell lines, using DCAF11 antibody (CAB15519) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.

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