Anti-Dapper homolog 3 Antibody (CAB8280)
- SKU:
- CAB8280
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
| Antibody Name: | DACT3 Rabbit Polyclonal Antibody |
| Antibody SKU: | CAB8280 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human DACT3 (NP_659493.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | MCF7, 293T, SH-SY5Y, Mouse heart, Mouse brain, Mouse bone marrow, Mouse liver, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human DACT3 (NP_659493.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MIRA FSFP VSPE RGRL RGWL EGSL AGLC ELHW LRER QEYR VQQA LRLA QPGM GGAE AEDE EDAD EDED AAAA RRAA AALE EQLE ALPG LVWD LGQQ LGDL SLES GGLE QESG RSSG FYED PSST GGPD SPPS TFCG DSGF SGSS SYGR LGPS EPRG IYAS |
| Gene ID: | 147906 |
| Uniprot: | Q96B18 |
| Cellular Location: | |
| Calculated MW: | 64kDa |
| Observed MW: | 75kDa |
| Synonyms: | DACT3, DAPPER3, RRR1 |
| Background: |
| UniProt Protein Function: | DACT3: May be involved in regulation of intracellular signaling pathways during development. Specifically thought to play a role in canonical and/or non-canonical Wnt signaling pathways through interaction with DSH (Dishevelled) family proteins. Belongs to the dapper family. |
| UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 19q13.32 Cellular Component: cytoplasm Molecular Function:identical protein binding; protein kinase C binding; protein kinase A binding Biological Process: Wnt receptor signaling pathway; negative regulation of Wnt receptor signaling pathway; negative regulation of cell growth |
| UniProt Code: | Q96B18 |
| NCBI GenInfo Identifier: | 119368655 |
| NCBI Gene ID: | 147906 |
| NCBI Accession: | Q96B18.2 |
| UniProt Related Accession: | Q96B18 |
| Molecular Weight: | |
| NCBI Full Name: | Dapper homolog 3 |
| NCBI Synonym Full Names: | dishevelled binding antagonist of beta catenin 3 |
| NCBI Official Symbol: | DACT3 |
| NCBI Official Synonym Symbols: | RRR1; DAPPER3 |
| NCBI Protein Information: | dapper homolog 3 |
| UniProt Protein Name: | Dapper homolog 3 |
| UniProt Synonym Protein Names: | Antagonist of beta-catenin Dapper homolog 3; Arginine-rich region 1 protein; Dapper antagonist of catenin 3 |
| Protein Family: | Dapper |
| UniProt Gene Name: | DACT3 |
| UniProt Entry Name: | DACT3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using DACT3 antibody (CAB8280) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 60s. |
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