Anti-Cytokeratin 7 Antibody (CAB4765)
- SKU:
- CAB4765
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
| Antibody Name: | Anti-Cytokeratin 7 Antibody |
| Antibody SKU: | CAB4765 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Cytokeratin 7 |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, A-549, Mouse lung, Mouse kidney, Rat kidney |
| Immunogen: | A synthesized peptide derived from human Cytokeratin 7 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 3855 |
| Uniprot: | P08729 |
| Cellular Location: | |
| Calculated MW: | 51kDa |
| Observed MW: | 52KDa |
| Synonyms: | CK7, K2C7, K7, SCL |
| Background: | The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | K7: a type II cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Phosphorylation of keratins at specific sites affects their organization, assembly dynamics, and their interaction with signaling molecules. Specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. |
| UniProt Protein Details: | Protein type:Cytoskeletal Chromosomal Location of Human Ortholog: 12q13.13 Cellular Component: cytoplasm; keratin filament; intermediate filament; nucleus Molecular Function:protein binding; structural molecule activity Biological Process: viral reproduction |
| NCBI Summary: | The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P08729 |
| NCBI GenInfo Identifier: | 67782365 |
| NCBI Gene ID: | 3855 |
| NCBI Accession: | NP_005547.3 |
| UniProt Secondary Accession: | P08729,Q92676, Q9BUD8, Q9Y3R7, |
| UniProt Related Accession: | P08729 |
| Molecular Weight: | 51,386 Da |
| NCBI Full Name: | keratin, type II cytoskeletal 7 |
| NCBI Synonym Full Names: | keratin 7 |
| NCBI Official Symbol: | KRT7 |
| NCBI Official Synonym Symbols: | K7; CK7; SCL; K2C7 |
| NCBI Protein Information: | keratin, type II cytoskeletal 7; CK-7; keratin-7; sarcolectin; cytokeratin 7; cytokeratin-7; type-II keratin Kb7; type II mesothelial keratin K7; keratin, 55K type II cytoskeletal; keratin, simple epithelial type I, K7 |
| UniProt Protein Name: | Keratin, type II cytoskeletal 7 |
| UniProt Synonym Protein Names: | Cytokeratin-7; CK-7; Keratin-7; K7; Sarcolectin; Type-II keratin Kb7 |
| Protein Family: | Keratin |
| UniProt Gene Name: | KRT7 |
| UniProt Entry Name: | K2C7_HUMAN |
 | Western blot - Cytokeratin 7 Rabbit mAb (CAB4765) |
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