Anti-CYSLTR2 Antibody (CAB16556)
- SKU:
- CAB16556
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-CYSLTR2 Antibody |
| Antibody SKU: | CAB16556 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human CYSLTR2 (NP_001295394.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | mouse kidney |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human CYSLTR2 (NP_001295394.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | TMNY IALV VGCL LPFF TLSI CYLL IIRV LLKV EVPE SGLR VSHR KALT TIII TLII FFLC FLPY HTLR TVHL TTWK VGLC KDRL HKAL VITL ALAA ANAC FNPL LYYF AGEN FKDR LKSA LRKG HPQK AKTK CVFP VSVW LRKE TRV |
| Gene ID: | 57105 |
| Uniprot: | Q9NS75 |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
| Calculated MW: | 39kDa |
| Observed MW: | 40kDa |
| Synonyms: | CYSLTR2, CYSLT2, CYSLT2R, GPCR21, HG57, HPN321, KPG_011, PSEC0146, hGPCR21 |
| Background: | The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR1. This encoded receptor is a member of the superfamily of G protein-coupled receptors. It seems to play a major role in endocrine and cardiovascular systems. |
| UniProt Protein Function: | Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Stimulation by BAY u9773, a partial agonist, induces specific contractions of pulmonary veins and might also have an indirect role in the relaxation of the pulmonary vascular endothelium. The rank order of affinities for the leukotrienes is LTC4 = LTD4 >> LTE4. |
| NCBI Summary: | The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR1. This encoded receptor is a member of the superfamily of G protein-coupled receptors. It seems to play a major role in endocrine and cardiovascular systems. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9NS75 |
| NCBI GenInfo Identifier: | 818213437 |
| NCBI Gene ID: | 57105 |
| NCBI Accession: | NP_001295394.1 |
| UniProt Secondary Accession: | Q9NS75,Q9HCQ2, |
| UniProt Related Accession: | Q9NS75 |
| Molecular Weight: | 35 KD |
| NCBI Full Name: | cysteinyl leukotriene receptor 2 |
| NCBI Synonym Full Names: | cysteinyl leukotriene receptor 2 |
| NCBI Official Symbol: | CYSLTR2 |
| NCBI Official Synonym Symbols: | HG57; CYSLT2; GPCR21; HPN321; CYSLT2R; KPG_011; hGPCR21; PSEC0146 |
| NCBI Protein Information: | cysteinyl leukotriene receptor 2 |
| UniProt Protein Name: | Cysteinyl leukotriene receptor 2 |
| UniProt Synonym Protein Names: | G-protein coupled receptor GPCR21; hGPCR21; G-protein coupled receptor HG57; HPN321 |
| UniProt Gene Name: | CYSLTR2 |
 | Western blot analysis of extracts of mouse kidney, using CYSLTR2 antibody (CAB16556) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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