Anti-Cyclin I Antibody (CAB17623)

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SKU:
CAB17623
Product type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Frequently bought together:

Description

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Antibody Name:Anti-Cyclin I Antibody
Antibody SKU:CAB17623
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 257-377 of human Cyclin I (NP_006826.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:BxPC-3, Rat spleen
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 257-377 of human Cyclin I (NP_006826.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:NSVY VYRP LKHT LVTC DKGV FRLH PSSV PGPD FSKD NSKP EVPV RGTA AFYH HLPA ASGC KQTS TKRK VEEM EVDD FYDG IKRL YNED NVSE NVGS VCGT DLSR QEGH ASPC PPLQ PVSV M
Gene ID:10983
Uniprot:Q14094
Cellular Location:
Calculated MW:40kDa/42kDa
Observed MW:43kDa
Anti-Cyclin I Antibody (CAB17623)Western blot - Cyclin I Rabbit pAb (CAB17623)
Synonyms:CCNI, CCNI1, CYC1, CYI, cyclin-I
Background:The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin shows the highest similarity with cyclin G. The transcript of this gene was found to be expressed constantly during cell cycle progression. [provided by RefSeq, Jan 2017]
UniProt Protein Function:CCNI: belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin shows the highest similarity with cyclin G. The transcript of this gene was found to be expressed constantly during cell cycle progression. The function of this cyclin has not yet been determined. [provided by RefSeq, Jul 2008]
UniProt Protein Details:

Protein type:Cell cycle regulation

Chromosomal Location of Human Ortholog: 4q21.1

Biological Process: regulation of cell cycle; spermatogenesis

NCBI Summary:The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin shows the highest similarity with cyclin G. The transcript of this gene was found to be expressed constantly during cell cycle progression. [provided by RefSeq, Jan 2017]
UniProt Code:Q14094
NCBI GenInfo Identifier:9296954
NCBI Gene ID:10983
NCBI Accession:Q14094.1
UniProt Related Accession:Q14094
Molecular Weight:
NCBI Full Name:Cyclin-I
NCBI Synonym Full Names:cyclin I
NCBI Official Symbol:CCNI  
NCBI Official Synonym Symbols:CYI; CYC1; CCNI1  
NCBI Protein Information:cyclin-I
UniProt Protein Name:Cyclin-I
Protein Family:Cyclin
UniProt Gene Name:CCNI  
UniProt Entry Name:CCNI_HUMAN

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