Anti-Cyclin G1 Antibody (CAB14713)
- SKU:
- CAB14713
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| Antibody Name: | Anti-Cyclin G1 Antibody |
| Antibody SKU: | CAB14713 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-295 of human Cyclin G1 (NP_004051.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | Mouse skeletal muscle |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-295 of human Cyclin G1 (NP_004051.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MIEV LTTT DSQK LLHQ LNAL LEQE SRCQ PKVC GLRL IESA HDNG LRMT ARLR DFEV KDLL SLTQ FFGF DTET FSLA VNLL DRFL SKMK VQPK HLGC VGLS CFYL AVKS IEEE RNVP LATD LIRI SQYR FTVS DLMR MEKI VLEK VCWK VKAT TAFQ FLQL YYSL LQEN LPLE RRNS INFE RLEA QLKA CHCR IIFS KAKP SVLA LSII ALEI QAQK CVEL TEGI ECLQ KHSK INGR DLTF WQEL VSKC LTEY SSNK CSKP NVQK LKWI VSGR TARQ LKHS YYRI THLP TIPE MVP |
| Gene ID: | 900 |
| Uniprot: | P51959 |
| Cellular Location: | Nucleus |
| Calculated MW: | 18kDa/34kDa |
| Observed MW: | 36kDa |
| Synonyms: | CCNG1, CCNG, cyclin-G1 |
| Background: | The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The protein encoded by this gene is a member of the cyclin family and contains the cyclin box. The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene. |
| UniProt Protein Function: | CCNG1: May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation. Belongs to the cyclin family. Cyclin G subfamily. |
| UniProt Protein Details: | Protein type:Cell cycle regulation Chromosomal Location of Human Ortholog: 5q32-q34 Cellular Component: nucleoplasm Molecular Function:protein binding Biological Process: regulation of cyclin-dependent protein kinase activity |
| NCBI Summary: | The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The protein encoded by this gene is a member of the cyclin family and contains the cyclin box. The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members. Transcriptional activation of this gene can be induced by tumor protein p53. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P51959 |
| NCBI GenInfo Identifier: | 2506334 |
| NCBI Gene ID: | 900 |
| NCBI Accession: | P51959.2 |
| UniProt Secondary Accession: | P51959,Q15757, Q96L32, B2R7B2, B4DLW7, D3DQK7, |
| UniProt Related Accession: | P51959 |
| Molecular Weight: | 18,769 Da |
| NCBI Full Name: | Cyclin-G1 |
| NCBI Synonym Full Names: | cyclin G1 |
| NCBI Official Symbol: | CCNG1 |
| NCBI Official Synonym Symbols: | CCNG |
| NCBI Protein Information: | cyclin-G1 |
| UniProt Protein Name: | Cyclin-G1 |
| Protein Family: | Cyclin |
| UniProt Gene Name: | CCNG1 |
| UniProt Entry Name: | CCNG1_HUMAN |
 | Western blot analysis of extracts of mouse skeletal muscle, using Cyclin G1 antibody (CAB14713) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
 | Immunofluorescence analysis of HeLa cells using Cyclin G1 antibody (CAB14713). |
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