Anti-Cyclin B2 Antibody (CAB7956)

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SKU:
CAB7956
Product type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
HsT17299
Frequently bought together:

Description

Product Name:Cyclin B2 Rabbit mAb
Product Code:CAB7956
Size:20uL, 50uL, 100uL
Synonyms:HsT17299
Applications:WB, IHC, IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human Cyclin B2
Applications:WB, IHC, IF
Recommended Dilutions:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:Rat testis
Immunogen:A synthesized peptide derived from human Cyclin B2
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:9133
Uniprot:O95067
Calculated MW:45kDa
Observed MW:45KDa
UniProt Protein Function:CCNB2: Essential for the control of the cell cycle at the G2/M (mitosis) transition. Belongs to the cyclin family. Cyclin AB subfamily.
UniProt Protein Details:

Protein type:Cell cycle regulation

Chromosomal Location of Human Ortholog: 15q22.2

Cellular Component: microtubule cytoskeleton; nucleoplasm; centrosome; membrane; cytosol

Molecular Function:protein binding; protein kinase binding

Biological Process: mitosis; thymus development; cell division; regulation of cell cycle; in utero embryonic development; mitotic nuclear envelope disassembly; T cell homeostasis; regulation of cyclin-dependent protein kinase activity; mitotic cell cycle; G2/M transition of mitotic cell cycle; growth

NCBI Summary:Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control. [provided by RefSeq, Jul 2008]
UniProt Code:O95067
NCBI GenInfo Identifier:5921731
NCBI Gene ID:9133
NCBI Accession:O95067.1
UniProt Related Accession:O95067
Molecular Weight:~ 45kDa
NCBI Full Name:G2/mitotic-specific cyclin-B2
NCBI Synonym Full Names:cyclin B2
NCBI Official Symbol:CCNB2  
NCBI Official Synonym Symbols:HsT17299  
NCBI Protein Information:G2/mitotic-specific cyclin-B2
UniProt Protein Name:G2/mitotic-specific cyclin-B2
Protein Family:Light-harvesting protein
UniProt Gene Name:CCNB2  
UniProt Entry Name:CCNB2_HUMAN

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