Anti-CYBRD1 Antibody (CAB17215)
- SKU:
- CAB17215
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| Antibody Name: | Anti-CYBRD1 Antibody |
| Antibody SKU: | CAB17215 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 215-286 of human CYBRD1 (NP_079119.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | HT-29, A-431 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 215-286 of human CYBRD1 (NP_079119.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | IFWI VTRP QWKR PKEP NSTI LHPN GGTE QGAR GSMP AYSG NNMD KSDS ELNS EVAA RKRN LALD EAGQ RSTM |
| Gene ID: | 79901 |
| Uniprot: | Q53TN4 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 36kDa |
 | Western blot - CYBRD1 Rabbit pAb (CAB17215) |
| Synonyms: | CYBRD1, CYB561A2, CYBRD1 |
| Background: | This gene is a member of the cytochrome b(561) family that encodes an iron-regulated protein. It highly expressed in the duodenal brush border membrane. It has ferric reductase activity and is believed to play a physiological role in dietary iron absorption. |
| UniProt Protein Function: | CYBRD1: Ferric-chelate reductase that reduces Fe(3+) to Fe(2+). Present at the brush border of duodenal enterocytes where it probably reduces dietary Fe(3+) thereby facilitating its transport into the mucosal cells. Uses ascorbate as electron donor. May be involved in extracellular ascorbate recycling in erythrocyte membranes. May also act as a ferrireductase in airway epithelial cells. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Membrane protein, integral; Transporter, ion channel; Transporter; Membrane protein, multi-pass; EC 1.-.-.-; Transporter, iron; Oxidoreductase Chromosomal Location of Human Ortholog: 2q31.1 Cellular Component: brush border membrane; integral to membrane; plasma membrane Molecular Function:oxidoreductase activity, oxidizing metal ions; metal ion binding; ferric-chelate reductase activity Biological Process: cellular iron ion homeostasis; response to iron ion; transmembrane transport |
| NCBI Summary: | This gene is a member of the cytochrome b(561) family that encodes an iron-regulated protein. It highly expressed in the duodenal brush border membrane. It has ferric reductase activity and is believed to play a physiological role in dietary iron absorption. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q53TN4 |
| NCBI GenInfo Identifier: | 74726934 |
| NCBI Gene ID: | 79901 |
| NCBI Accession: | Q53TN4.1 |
| UniProt Secondary Accession: | Q53TN4,Q6KC16, Q6KC17, Q6P147, Q6ZR51, Q9H0Q8, Q9H5G5 B2RE79, B4DWD7, |
| UniProt Related Accession: | Q53TN4 |
| Molecular Weight: | 25,087 Da |
| NCBI Full Name: | Cytochrome b reductase 1 |
| NCBI Synonym Full Names: | cytochrome b reductase 1 |
| NCBI Official Symbol: | CYBRD1 |
| NCBI Official Synonym Symbols: | DCYTB; FRRS3; CYB561A2 |
| NCBI Protein Information: | cytochrome b reductase 1; duodenal cytochrome b; ferric-chelate reductase 3; cytochrome b561 family, member A2 |
| UniProt Protein Name: | Cytochrome b reductase 1 |
| UniProt Synonym Protein Names: | Duodenal cytochrome b; Ferric-chelate reductase 3 |
| Protein Family: | Cytochrome b reductase |
| UniProt Gene Name: | CYBRD1 |
| UniProt Entry Name: | CYBR1_HUMAN |
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